O'Shea James P, Whalen Stephen, Branco Daniel M, Petrovich Nicole M, Knierim Kyle E, Golby Alexandra J
Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Int J Med Robot. 2006 Mar;2(1):75-83. doi: 10.1002/rcs.82.
The ability to effectively identify eloquent cortex in close proximity to brain tumours is a critical component of surgical planning prior to resection. The use of electrocortical stimulation testing (ECS) during awake neurosurgical procedures remains the gold standard for mapping functional areas, yet the preoperative use of non-invasive brain imaging techniques such as fMRI are gaining popularity as supplemental surgical planning tools. In addition, the intraoperative three-dimensional display of fMRI findings co-registered to structural imaging data maximizes the utility of the preoperative mapping for the surgeon. Advances in these techniques have the potential to limit the size and duration of craniotomies as well as the strain placed on the patient, but more research accurately demonstrating their efficacy is required. In this paper, we demonstrate the integration of preoperative fMRI within a neuronavigation system to aid in surgical planning, as well as the integration of these fMRI data with intraoperative ECS mapping results into a three-dimensional dataset for the purpose of cross-validation.
在切除手术前，有效识别紧邻脑肿瘤的明确皮质的能力是手术规划的关键组成部分。在清醒神经外科手术过程中使用皮质电刺激测试（ECS）仍然是绘制功能区的金标准，然而，诸如功能磁共振成像（fMRI）等非侵入性脑成像技术在术前作为辅助手术规划工具正越来越受欢迎。此外，将fMRI结果与结构成像数据共同配准的术中三维显示，最大限度地提高了术前图谱对外科医生的效用。这些技术的进步有可能限制开颅手术的规模和持续时间以及对患者造成的压力，但需要更多研究来准确证明其疗效。在本文中，我们展示了术前fMRI在神经导航系统中的整合，以辅助手术规划，以及将这些fMRI数据与术中ECS图谱结果整合到一个三维数据集中，以进行交叉验证。
