Swanson Sara J, Sabsevitz David S, Hammeke Thomas A, Binder Jeffrey R
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Neuropsychol Rev. 2007 Dec;17(4):491-504. doi: 10.1007/s11065-007-9050-x. Epub 2007 Nov 16.
Functional magnetic resonance imaging (fMRI) has revolutionized our understanding of functional networks and cerebral organization in both normal and pathological brains. In the present review, we describe the use of fMRI for mapping language in epilepsy patients prior to surgical intervention including a discussion of methodological issues and task design, comparisons between fMRI and the intracarotid sodium amobarbital test, fMRI studies of language reorganization, and the use of fMRI laterality indexes to predict outcome after anterior temporal lobectomy.
功能磁共振成像(fMRI)彻底改变了我们对正常和病理大脑中功能网络和脑组织的理解。在本综述中,我们描述了fMRI在癫痫患者手术干预前用于语言映射的情况,包括方法学问题和任务设计的讨论、fMRI与颈内动脉注射阿米妥钠试验的比较、语言重组的fMRI研究,以及使用fMRI偏侧指数预测颞叶前切除术的结果。