Kaletina N I, Kaletin G I, Skal'nyĭ A V
Sud Med Ekspert. 2007 Mar-Apr;50(2):38-42.
It is well known that a toxic effect of some medicines is the result of their in vivo interactions with trace elements leading to disturbance of trace element balance in the living body. The Mossbauer spectrometry technique has been used for toxicochemical evaluation of iron-bearing medicines. This method can be used in forensic toxicology. We studied composition of trace elements in the hair of children living in Macedonia: in polluted territory (the town of Veles, the study group) versus in unpolluted one (Ivankovci village, the control group). AES-ICP and ICP-MS techniques were used. We discovered that the hair of children living in the polluted territory contain significantly elevated concentrations of Pb (in 43% cases), Hg, Ni (14%), Cd (21%), Cu (16%), Sn, As, Na, Se and subnormal concentrations of Mg (in 51% cases), Mn, Cr and Li.
众所周知，某些药物的毒性作用是其在体内与微量元素相互作用，导致生物体内微量元素平衡紊乱的结果。穆斯堡尔光谱技术已用于含铁药物的毒化学评估。该方法可用于法医毒理学。我们研究了生活在马其顿的儿童头发中的微量元素组成：污染地区（韦莱斯镇，研究组）与未污染地区（伊万科夫奇村，对照组）。使用了AES-ICP和ICP-MS技术。我们发现，生活在污染地区的儿童头发中铅（43%的案例）、汞、镍（14%）、镉（21%）、铜（16%）、锡、砷、钠、硒的浓度显著升高，而镁（51%的案例）、锰、铬和锂的浓度低于正常水平。
