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[2型糖尿病合并动脉高血压患者的脑灌注]

[Cerebral perfusion in patients with arterial hypertension associated with type 2 diabetes].

作者信息

Efimova I Iu, Belokopytova N V, Triss S V, Lishmanov Iu B

出版信息

Klin Med (Mosk). 2007;85(3):33-7.

PMID:17523401
Abstract

The aim of the study was to assess cerebral perfusion (CP) in patients with arterial hypertension in combination with type II diabetes. The subjects were 57 patients with stage II AH (mean age 51.6 +/- 5.7 years), among who there were 33 patients without disturbances in carbohydrate exchange and 24 patients with compensated or subcompensated type II diabetes. All the patients underwent single-photon emission computed tomography of the brain with 99m Tchexamethylpropyleneamineoxime. The study showed that patients suffering from AH with or without type II diabetes had signs of cerebral hypoperfusion and lowered cerebrovascular reserve even in the absence of focal neurological symptoms. Disturbances in cerebral perfusion were more prominent in patients suffering from AH with type II diabetes vs. patients without carbohydrate exchange disorder.

摘要

该研究的目的是评估患有动脉高血压合并II型糖尿病患者的脑灌注(CP)情况。研究对象为57例II期动脉高血压患者(平均年龄51.6±5.7岁),其中33例碳水化合物代谢无紊乱,24例为代偿性或亚代偿性II型糖尿病患者。所有患者均接受了用99m锝六甲基丙烯胺肟进行的脑部单光子发射计算机断层扫描。研究表明,患有或未患有II型糖尿病的动脉高血压患者即使在没有局灶性神经症状的情况下也有脑灌注不足和脑血管储备降低的迹象。与碳水化合物代谢无紊乱的患者相比,患有II型糖尿病的动脉高血压患者脑灌注紊乱更为明显。

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