Konstantinopoulos P A, Goldsztein H, Dezube B J, Pantanowitz L
Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
J Laryngol Otol. 2008 Sep;122(9):993-7. doi: 10.1017/S0022215107008705. Epub 2007 May 25.
Oral involvement is a common manifestation of acquired immunodeficiency syndrome related Kaposi's sarcoma, and it occurs in approximately one-third of afflicted patients.
We report an unusual case of Kaposi's sarcoma of the hard palate which invaded the underlying maxillary bone.
The patient underwent excisional biopsy and was subsequently treated with localised radiation and systemic chemotherapy including liposomal doxorubicin.
The presentation, differential diagnosis, radiographic appearance and management of this serious complication are discussed. Our case highlights the need for a multidisciplinary approach, consisting of ENT, oncology and infectious disease consultation, to ensure appropriate management of maxillofacial, intraosseous, acquired immunodeficiency syndrome related Kaposi's sarcoma.
口腔受累是获得性免疫缺陷综合征相关卡波西肉瘤的常见表现，约三分之一的患病患者会出现这种情况。
我们报告了一例罕见的硬腭卡波西肉瘤病例，该肿瘤侵犯了下方的上颌骨。
患者接受了切除活检，随后接受了局部放疗和包括脂质体阿霉素在内的全身化疗。
讨论了这种严重并发症的临床表现、鉴别诊断、影像学表现及治疗。我们的病例强调了需要多学科方法，包括耳鼻喉科、肿瘤学和传染病会诊，以确保对与获得性免疫缺陷综合征相关的颌面、骨内卡波西肉瘤进行适当治疗。
