Grifone Raphaëlle, Kelly Robert G
Developmental Biology Institute of Marseilles - Luminy, Inserm Avenir Group, UMR 6216 CNRS-Université de la Méditerranée, Campus de Luminy Case 907, 13288 Marseilles Cedex 9, France.
Trends Genet. 2007 Aug;23(8):365-9. doi: 10.1016/j.tig.2007.05.002. Epub 2007 May 23.
Branchiomeric craniofacial muscles differ from all other skeletal muscles with respect to embryological origin, motor innervation and upstream activators of myogenesis. A series of recent studies has revealed a striking juxtaposition and overlapping genetic program of craniofacial skeletal muscle progenitor cells with a population of cells giving rise to cardiac muscle. The divergent myogenic fates of adjacent progenitor cells revealed by these data provide a new framework for the study of craniofacial myogenesis.
鳃弓源性颅面部肌肉在胚胎起源、运动神经支配及肌生成的上游激活因子方面与所有其他骨骼肌不同。最近的一系列研究揭示了颅面部骨骼肌祖细胞与一群产生心肌的细胞在基因程序上存在显著的并列和重叠。这些数据所揭示的相邻祖细胞不同的肌源性命运为颅面部肌生成的研究提供了一个新框架。