通过Humphrey矩阵频率加倍技术视野检查发现的局限性视网膜神经纤维层缺损和视野异常。
Localized retinal nerve fiber layer defects and visual field abnormalities by humphrey matrix frequency doubling technology perimetry.
作者信息
Lee Min Joung, Kim Dong Myung, Jeoung Jin Wook, Hwang Seung-Sik, Kim Tae Woo, Park Ki Ho
机构信息
Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
出版信息
Am J Ophthalmol. 2007 Jun;143(6):1056-8. doi: 10.1016/j.ajo.2007.02.021.
PURPOSE
To investigate the ability of frequency doubling technology (FDT) perimetry to identify eyes with a localized retinal nerve fiber layer (RNFL) defect and normal Humphrey C30-2 SITA-Standard visual field (HVF).
DESIGN
Retrospective case-control study.
METHODS
Fifty-four eyes were divided into two groups, an abnormal (n = 29) and a normal (n = 25) FDT perimetry group. Approximation of the RNFL defect to the macula (angle alpha) and width of the defect (angle beta) were measured by RNFL photograph and compared between two groups.
RESULTS
Angle alpha and angle beta were significantly different between two groups (P < .001 by Mann-Whitney U test, respectively). A multivariate logistic regression analysis demonstrated that only angle beta was significantly associated with FDT perimetry abnormalities (P = .002).
CONCLUSIONS
Only 53.7% of the eyes with a localized RNFL defect and normal HVF had visual field abnormalities identified by FDT perimetry. Width of the RNFL defect was more strongly associated with FDT perimetry abnormalities than location of the defect.
目的
研究倍频技术（FDT）视野检查识别存在局限性视网膜神经纤维层（RNFL）缺损且 Humphrey C30 - 2 SITA - 标准视野（HVF）正常的眼睛的能力。
设计
回顾性病例对照研究。
方法
54只眼睛被分为两组，即 FDT 视野检查异常组（n = 29）和正常组（n = 25）。通过 RNFL 照片测量 RNFL 缺损与黄斑的接近程度（α角）和缺损宽度（β角），并在两组之间进行比较。
结果
两组之间的α角和β角存在显著差异（分别通过 Mann - Whitney U 检验，P <.001）。多因素逻辑回归分析表明，只有β角与 FDT 视野检查异常显著相关（P =.002）。
结论
在存在局限性 RNFL 缺损且 HVF 正常的眼睛中，只有 53.7%通过 FDT 视野检查发现视野异常。RNFL 缺损的宽度比缺损位置与 FDT 视野检查异常的相关性更强。
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