与年龄匹配的对照组相比，对婴儿型眼球震颤综合征患者进行临床对比敏感度测试。
Clinical contrast sensitivity testing in patients with infantile nystagmus syndrome compared with age-matched controls.
作者信息
Hertle Richard W, Reese Matthew
机构信息
Division of Ophthalmology, Children's Hospital of Pittsburgh, Pennsylvania 15213, USA.
出版信息
Am J Ophthalmol. 2007 Jun;143(6):1063-5. doi: 10.1016/j.ajo.2007.02.028.
PURPOSE
To compare contrast sensitivity using a commercially available technique between patients with infantile nystagmus syndrome (INS) and controls.
DESIGN
Prospective, comparative case series.
METHODS
The functional acuity contrast test (FACT) was used binocularly in patients with INS and aged-matched controls with best acuity under normal lighting using a progression of high-quality sine wave grating size changes with increasing spatial frequencies.
RESULTS
Nine INS patients aged 5 to 11 years and 25 controls were tested. The INS patients' best binocular acuity ranged from 20/125 to 20/30, and that of the controls was 20/25 or better. When compared with age-matched controls, INS patients displayed deficiencies in contrast sensitivity syndrome using the FACT test.
CONCLUSIONS
The FACT or a similar testing system may have potential as a commercially available outcome measure in clinical trials in patients with INS.
目的
使用一种市售技术比较婴儿型眼球震颤综合征（INS）患者与对照组之间的对比敏感度。
设计
前瞻性、比较性病例系列研究。
方法
对INS患者和年龄匹配的对照组进行双眼功能视力对比测试（FACT），在正常照明条件下，使用一系列随着空间频率增加而变化的高质量正弦波光栅大小，以获得最佳视力。
结果
对9例年龄在5至11岁的INS患者和25名对照组进行了测试。INS患者的最佳双眼视力范围为20/125至20/30，而对照组为20/25或更好。与年龄匹配的对照组相比，INS患者在使用FACT测试时显示出对比敏感度综合征的缺陷。
结论
FACT或类似的测试系统可能有潜力作为INS患者临床试验中一种市售的结果测量方法。
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