Kang Shin J, Wojno Ted H, Grossniklaus Hans E
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
Am J Ophthalmol. 2007 Jun;143(6):1065-7. doi: 10.1016/j.ajo.2007.02.027.
To report a case of proliferating trichilemmal cyst in a 55-year-old woman.
Observational case report.
A 55-year-old woman sought treatment for a mass in the right upper eyelid. The lesion was excised twice previously, and recurred. The mass was reexcised and examined histopathologically.
Light microscopy showed a cystic lesion lined by stratified squamous epithelium with a compact layer of eosinophilic keratin without granular cell layer. There was no atypia, mitosis, or stromal invasion.
Although proliferating trichilemmal cyst shows benign histopathologic features, clinical manifestations may mimic those of more aggressive tumors with local recurrences or distant metastasis. Wide excision of the lesion and close long-term follow-up is recommended.
报告一例55岁女性的增生性外毛根鞘囊肿。
观察性病例报告。
一名55岁女性因右上眼睑肿物寻求治疗。该病变先前已切除两次，但复发。肿物再次切除并进行组织病理学检查。
光镜下显示一个囊性病变，内衬复层鳞状上皮，有一层致密的嗜酸性角蛋白，无颗粒细胞层。未见异型性、有丝分裂或间质浸润。
尽管增生性外毛根鞘囊肿表现出良性组织病理学特征，但其临床表现可能类似于更具侵袭性的肿瘤，可出现局部复发或远处转移。建议广泛切除病变并进行长期密切随访。
