Daley Amanda J, Crank Helen, Mutrie Nanette, Saxton John M, Coleman Robert
The Department of Primary Care and General Practice, The Medical School, Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, UK.
Eur J Oncol Nurs. 2007 Dec;11(5):392-9. doi: 10.1016/j.ejon.2007.03.001. Epub 2007 May 24.
We describe adherence to a three group randomised controlled trial that involved aerobic exercise therapy (N=34) and exercise-placebo intervention (N=36) or usual care (N=38) in women treated for breast cancer. We also investigated relationships between routes of trial recruitment, socio-economic characteristics, health behaviours, cancer treatment regimen(s) and subsequent adherence to the interventions. Women who had completed breast cancer treatment 12-36 months previously were randomised to one of the groups. The intervention groups attended an exercise facility three times per week for eight weeks. A total of 77% of the aerobic exercise therapy and 88.9% of the exercise-placebo groups attended at least 70% of prescribed sessions. The percentage of women achieving 30min of aerobic exercise per session steadily increased during the intervention but many women were not able to achieve this goal. Routes of trial recruitment, socio-economic characteristics, health behaviours and cancer treatment regimen(s) were not related to intervention. Exercise therapy participants were able to comply with the progressive nature of the aerobic exercise intervention, although some women were not able to achieve 30min of aerobic exercise per session by intervention completion. Research is still required to tease out all the potential determinants of exercise in this population.
我们描述了一项针对乳腺癌女性患者的三组随机对照试验的依从情况，该试验包括有氧运动疗法（N = 34）、运动安慰剂干预（N = 36）或常规护理（N = 38）。我们还研究了试验招募途径、社会经济特征、健康行为、癌症治疗方案与后续干预依从性之间的关系。此前12至36个月已完成乳腺癌治疗的女性被随机分配到其中一组。干预组每周到健身设施锻炼三次，共持续八周。有氧运动疗法组中77%的女性以及运动安慰剂组中88.9%的女性至少参加了规定疗程的70%。在干预期间，每次锻炼达到30分钟有氧运动的女性比例稳步上升，但许多女性未能实现这一目标。试验招募途径、社会经济特征、健康行为和癌症治疗方案与干预无关。运动疗法参与者能够遵循有氧运动干预的渐进性，尽管有些女性在干预结束时未能每次锻炼达到30分钟有氧运动。仍需开展研究以梳理出该人群运动的所有潜在决定因素。
