Chen J
Radiation Protection Bureau, Health Canada, Ottawa, Canada. jing_
Radiat Prot Dosimetry. 2007;126(1-4):445-8. doi: 10.1093/rpd/ncm089. Epub 2007 May 24.
Carbon ions were introduced to radiation therapy due to their special physical and radiobiological properties. In heavy ion therapy, specification of radiation quality is an important issue and rapid calculations are often required for treatment planning. Because radiation qualities are closely related to microdosimetric spectra and parameters, this study is intended to provide microdosimetric parameters of carbon track-segments in the energy range from 50 MeV to 5 GeV. Monte-Carlo techniques are used to simulate track-segments of carbon ions in water. Microdosimetric quantities (the dose mean lineal energies) are calculated for the two components of the track-segment: the track-core formed by energy deposition of carbon ions and the track-penumbra (an extended region around the track-core produced by energy deposition of secondary electrons).
由于碳离子具有特殊的物理和放射生物学特性,其已被引入放射治疗。在重离子治疗中,辐射质量的规范是一个重要问题,并且治疗计划通常需要快速计算。由于辐射质量与微剂量谱和参数密切相关,本研究旨在提供能量范围从50 MeV至5 GeV的碳粒子径迹段的微剂量参数。采用蒙特卡罗技术模拟碳离子在水中的径迹段。针对径迹段的两个组成部分计算微剂量学量(剂量平均线能量):由碳离子能量沉积形成的径迹核心,以及径迹半影(由二次电子能量沉积在径迹核心周围产生的扩展区域)。