Panico Lidia, Bartley Mel, Marmot Michael, Nazroo James Y, Sacker Amanda, Kelly Yvonne J
Department of Epidemiology & Public Health, University College London, London, UK.
Int J Epidemiol. 2007 Oct;36(5):1093-102. doi: 10.1093/ije/dym089. Epub 2007 May 24.
It is not clear how respiratory morbidity during early childhood varies across ethnic groups in the UK. This article seeks to determine whether asthma and wheeze illnesses during early childhood differ across ethnic groups and what factors explain observed differences.
Data from the UK Millennium Cohort Study on 14,630 children were analyzed from the second sweep of interviews. Parental interviews were conducted when the cohort member was aged approximately 3(1/2) years. Data collected included the occurrence of asthma and wheezing symptoms, biological and socio-economic factors and markers of cultural tradition.
At age 3, 12.3% (n = 1,902) of children had ever had asthma and 20.0% (n = 3,030) had wheezed in the last 12 months. 18.2% of Black Caribbean children and 5.0% of Bangladeshi children reported ever asthma compared with 11.6% of White children. 25.5% of Black Caribbean children and 8.7% of Bangladeshi reported recent wheeze compared with 19.4% of White children. After adjustments, the disadvantage in asthma and recent wheeze for Black Caribbeans was mostly explained by socio-economic factors (adjusted odds ratios (OR) for asthma 1.42, 95% confidence interval (CI) 0.96-2.09; recent wheeze 1.18, 0.85-1.64). The Bangladeshi advantage lost statistical significance, mostly due to adjustment for markers of cultural tradition (adjusted OR for asthma 0.40, 95% CI 0.15-1.09; recent wheeze 0.44, 0.18-1.19).
Our results point to the need to locate child health within the unique context of each ethnic group and to recognize that potential explanations for observed differences do not necessarily hold for all groups.
目前尚不清楚英国不同种族儿童期的呼吸道发病率如何变化。本文旨在确定不同种族儿童期哮喘和喘息疾病是否存在差异，以及哪些因素可以解释观察到的差异。
对英国千禧队列研究中14630名儿童第二次访谈的数据进行分析。当队列成员年龄约为3（1/2）岁时进行家长访谈。收集的数据包括哮喘和喘息症状的发生情况、生物学和社会经济因素以及文化传统标志。
3岁时，12.3%（n = 1902）的儿童曾患哮喘，20.0%（n = 3030）在过去12个月内有喘息症状。18.2%的加勒比黑人儿童和5.0%的孟加拉裔儿童报告曾患哮喘，而白人儿童的这一比例为11.6%。25.5%的加勒比黑人儿童和8.7%的孟加拉裔儿童报告近期有喘息症状，而白人儿童的这一比例为19.4%。调整后，加勒比黑人在哮喘和近期喘息方面的劣势主要由社会经济因素解释（哮喘调整后的优势比（OR）为1.42，95%置信区间（CI）为0.96 - 2.09；近期喘息为1.18，0.85 - 1.64）。孟加拉裔的优势失去了统计学意义，主要是由于对文化传统标志进行了调整（哮喘调整后的OR为0.40，95%CI为0.15 - 1.09；近期喘息为0.44，0.18 - 1.19）。
我们的结果表明，需要在每个种族群体的独特背景下看待儿童健康，并认识到观察到的差异的潜在解释不一定适用于所有群体。
