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1985年至2003年密歇根州一系列与麻醉相关的孕产妇死亡事件。

A series of anesthesia-related maternal deaths in Michigan, 1985-2003.

作者信息

Mhyre Jill M, Riesner Monica N, Polley Linda S, Naughton Norah N

机构信息

Department of Anesthesiology, University of Michigan Health System, Ann Arbor 48109-0048, USA.

出版信息

Anesthesiology. 2007 Jun;106(6):1096-104. doi: 10.1097/01.anes.0000267592.34626.6b.

Abstract

BACKGROUND

Maternal Mortality Surveillance has been conducted by the State of Michigan since 1950, and anesthesia-related maternal deaths were most recently reviewed for the years 1972-1984.

METHODS

Records for pregnancy-associated deaths between 1985 and 2003 were reviewed to identify 25 cases associated with a perioperative arrest or major anesthetic complication. Four obstetric anesthesiologists independently classified these cases, and disagreements were resolved by discussion. Precise definitions of anesthesia-related and anesthesia-contributing maternal death were constructed. Anesthesia-related deaths were reviewed to identify the chain of medical errors or care management problems that contributed to each patient death.

RESULTS

Of 855 pregnancy-associated deaths, 8 were anesthesia-related and 7 were anesthesia-contributing. There were no deaths during induction of general anesthesia. Five resulted from hypoventilation or airway obstruction during emergence, extubation, or recovery. Lapses in either postoperative monitoring or anesthesiology supervision seemed to contribute to 5 of the 8 anesthesia-related deaths. Other characteristics common to these cases included obesity (n=6) and African-American race (n=6).

CONCLUSIONS

The 8 anesthesia-related and seven anesthesia-contributing maternal deaths in Michigan between 1985 and 2003 illustrate three key points. First, all anesthesia-related deaths from airway obstruction or hypoventilation took place during emergence and recovery, not during the induction of general anesthesia. Second, system errors played a role in the majority of cases. Of concern, lapses in postoperative monitoring and inadequate supervision by an anesthesiologist seemed to contribute to more than half of the deaths. Finally, this report confirms previous work that obesity and African-American race are important risk factors for anesthesia-related maternal mortality.

摘要

背景

自1950年以来,密歇根州一直在进行孕产妇死亡率监测,最近一次对1972 - 1984年期间与麻醉相关的孕产妇死亡情况进行了审查。

方法

对1985年至2003年期间与妊娠相关的死亡记录进行审查,以确定25例与围手术期心脏骤停或重大麻醉并发症相关的病例。四位产科麻醉医生对这些病例进行独立分类,分歧通过讨论解决。构建了与麻醉相关和促成麻醉的孕产妇死亡的精确定义。对与麻醉相关的死亡病例进行审查,以确定导致每位患者死亡的医疗差错或护理管理问题链。

结果

在855例与妊娠相关的死亡病例中,8例与麻醉相关,7例促成麻醉。全身麻醉诱导期间无死亡病例。5例死亡是由于苏醒、拔管或恢复期间通气不足或气道阻塞所致。术后监测或麻醉学监督失误似乎导致了8例与麻醉相关死亡病例中的5例。这些病例的其他共同特征包括肥胖(n = 6)和非裔美国人种族(n = 6)。

结论

1985年至2003年期间密歇根州的8例与麻醉相关和7例促成麻醉的孕产妇死亡说明了三个关键点。第一,所有因气道阻塞或通气不足导致的与麻醉相关的死亡均发生在苏醒和恢复期间,而非全身麻醉诱导期间。第二,系统错误在大多数病例中起了作用。令人担忧的是,术后监测失误和麻醉医生监督不足似乎导致了一半以上的死亡病例。最后,本报告证实了先前的研究结果,即肥胖和非裔美国人种族是与麻醉相关的孕产妇死亡的重要危险因素。

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