日本儿童急性髓系白血病伴t(8;21)患者中KIT基因N822突变常见：日本儿童AML协作研究组的一项研究 - Suppr

Suppr

超能文献

N822 mutation of KIT gene was frequent in pediatric acute myeloid leukemia patients with t(8;21) in Japan: a study of the Japanese childhood AML cooperative study group.

作者信息

Shimada A, Taki T, Kubota C, Itou T, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y

出版信息

Leukemia. 2007 Oct;21(10):2218-9. doi: 10.1038/sj.leu.2404766. Epub 2007 May 24.

DOI:10.1038/sj.leu.2404766

PMID:17525721

Abstract

摘要

相似文献

N822 mutation of KIT gene was frequent in pediatric acute myeloid leukemia patients with t(8;21) in Japan: a study of the Japanese childhood AML cooperative study group.日本儿童急性髓系白血病伴t(8;21)患者中KIT基因N822突变常见：日本儿童AML协作研究组的一项研究

Leukemia. 2007 Oct;21(10):2218-9. doi: 10.1038/sj.leu.2404766. Epub 2007 May 24.

Systemic mastocytosis associated with t(8;21) acute myeloid leukemia in a child: detection of the D816A mutation of KIT.儿童伴 t(8;21) 急性髓系白血病的系统性肥大细胞增生症：KIT 的 D816A 突变检测。

Pediatr Blood Cancer. 2012 Dec 15;59(7):1313-6. doi: 10.1002/pbc.24250. Epub 2012 Jul 27.

Two cell lines of t(8;21) acute myeloid leukemia with activating KIT exon 17 mutation: models for the 'second hit' hypothesis.

Leukemia. 2008 Sep;22(9):1792-4. doi: 10.1038/leu.2008.61. Epub 2008 Apr 3.

AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec.t(8;21)白血病中AML1-ETO与C-KIT突变/过表达：对白血病逐步发生及对格列卫反应的影响

Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1104-9. doi: 10.1073/pnas.0408831102. Epub 2005 Jan 13.

AML1-ETO9a is correlated with C-KIT overexpression/mutations and indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2.AML1-ETO9a与C-KIT过表达/突变相关，提示t(8;21)急性髓系白血病-M2患者预后不良。

Leukemia. 2009 Sep;23(9):1598-604. doi: 10.1038/leu.2009.104. Epub 2009 May 21.

Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: analysis of clinicopathologic features and activating c-kit mutations.系统性肥大细胞增多症伴相关克隆性血液系统非肥大细胞谱系疾病：临床病理特征及活化型c-kit突变分析

Am J Hematol. 2003 May;73(1):12-7. doi: 10.1002/ajh.10322.

A Novel KIT INDEL Mutation in Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1.伴有t(8;21)(q22;q22); RUNX1-RUNX1T1的急性髓系白血病中的一种新型KIT插入缺失突变

Ann Lab Med. 2016 Jul;36(4):371-4. doi: 10.3343/alm.2016.36.4.371.

Importance of c-kit mutation detection method sensitivity in prognostic analyses of t(8;21)(q22;q22) acute myeloid leukemia.c-kit 基因突变检测方法灵敏度在 t(8;21)(q22;q22) 急性髓系白血病预后分析中的重要性。

Leukemia. 2011 Sep;25(9):1423-32. doi: 10.1038/leu.2011.104. Epub 2011 May 24.

[Analysis of c-kit and JAK2 gene mutations in t(8;21) acute myeloid leukemia].t(8;21)急性髓系白血病中c-kit和JAK2基因突变分析

Zhonghua Xue Ye Xue Za Zhi. 2008 Dec;29(12):797-801.

FLT3-internal tandem duplication in a pediatric patient with t(8;21) acute myeloid leukemia.一名患有t(8;21)急性髓系白血病的儿科患者中的FLT3内部串联重复。

Cancer Genet Cytogenet. 2010 Dec;203(2):292-6. doi: 10.1016/j.cancergencyto.2010.07.130.

引用本文的文献

New C3H Kit cancer mouse model develops late-onset malignant mammary tumors with high penetrance.新型 C3H Kit 癌症小鼠模型可发展出具有高外显率的迟发性恶性乳腺肿瘤。

Sci Rep. 2022 Nov 17;12(1):19793. doi: 10.1038/s41598-022-23218-5.

Core binding factor acute myeloid leukemia: Advances in the heterogeneity of , , and mutations (Review).核心结合因子急性髓系白血病：CBFB、RUNX和NPM1突变异质性研究进展（综述）

Mol Clin Oncol. 2020 Aug;13(2):95-100. doi: 10.3892/mco.2020.2052. Epub 2020 May 25.

Prospective evaluation of prognostic impact of KIT mutations on acute myeloid leukemia with RUNX1-RUNX1T1 and CBFB-MYH11.前瞻性评估 KIT 突变对伴有 RUNX1-RUNX1T1 和 CBFB-MYH11 的急性髓系白血病的预后影响。

Blood Adv. 2020 Jan 14;4(1):66-75. doi: 10.1182/bloodadvances.2019000709.

Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML.在儿科合作研究中招募的新发急性髓细胞白血病的儿童患者中，核心结合因子 AML 中 KIT 突变的流行率和预后意义。

Blood. 2010 Mar 25;115(12):2372-9. doi: 10.1182/blood-2009-09-241075. Epub 2010 Jan 7.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验