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一项旨在改善门诊儿科处方模式的整群随机临床试验。

A cluster randomized clinical trial to improve prescribing patterns in ambulatory pediatrics.

作者信息

Davis Robert L, Wright Jeffrey, Chalmers Francie, Levenson Linda, Brown Julie C, Lozano Paula, Christakis Dimitri A

机构信息

Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, United States of America.

出版信息

PLoS Clin Trials. 2007 May 18;2(5):e25. doi: 10.1371/journal.pctr.0020025.

Abstract

OBJECTIVES

Having shown previously that an electronic prescription writer and decision support system improved pediatric prescribing behavior for otitis media in an academic clinic setting, we assessed whether point-of-care delivery of evidence could demonstrate similar effects for a wide range of other common pediatric conditions.

DESIGN

Cluster randomized controlled trial.

SETTING

A teaching clinic/clinical practice site and a primary care pediatric clinic serving a rural and semi-urban patient mix.

PARTICIPANTS

A total of 36 providers at the teaching clinic/practice site and eight providers at the private primary pediatric clinic.

INTERVENTION

An evidence-based message system that presented real-time evidence to providers based on prescribing practices for acute otitis media, allergic rhinitis, sinusitis, constipation, pharyngitis, croup, urticaria, and bronchiolitis.

OUTCOME MEASURES

The proportion of prescriptions dispensed in accordance with evidence.

RESULTS

The proportion of prescriptions dispensed in accordance with evidence improved four percentage points, from 38% at baseline to 42% following the intervention. The control group improved by one percentage point, from 39% at baseline to 40% at trial's conclusion. The adjusted difference between the intervention and control groups was 8% (95% confidence interval 1%, 15%). Intervention effectiveness did not decrease with time.

CONCLUSION

For common pediatric outpatient conditions, a point-of-care evidence-based prescription writer and decision support system was associated with significant improvements in prescribing practices.

摘要

目的

此前我们已表明,在学术诊所环境中,电子处方书写器和决策支持系统改善了中耳炎的儿科处方行为,我们评估了即时提供证据是否能对一系列其他常见儿科疾病产生类似效果。

设计

整群随机对照试验。

地点

一家教学诊所/临床实践点以及一家为农村和半城市患者群体服务的初级保健儿科诊所。

参与者

教学诊所/实践点共有36名医疗服务提供者,私立初级儿科诊所8名医疗服务提供者。

干预措施

一个基于证据的信息系统,根据急性中耳炎、过敏性鼻炎、鼻窦炎、便秘、咽炎、哮吼、荨麻疹和细支气管炎的处方实践,向医疗服务提供者呈现实时证据。

观察指标

按证据配药的处方比例。

结果

按证据配药的处方比例提高了4个百分点,从基线时的38%提高到干预后的42%。对照组提高了1个百分点,从基线时的39%提高到试验结束时的40%。干预组与对照组的调整差异为8%(95%置信区间1%,15%)。干预效果未随时间降低。

结论

对于常见的儿科门诊疾病,即时提供证据的处方书写器和决策支持系统与处方实践的显著改善相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bff9/1876598/a51c35cfa223/pctr.0020025.g001.jpg

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