Khan N, Tyagi S P, Salahuddin A
Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University.
Indian J Pathol Microbiol. 1991 Apr;34(2):126-30.
Serum cholinesterase (ChE) and Lactate dehydrogenase (LDH) activities were estimated in 40 cases of carcinoma breast, 25 cases of benign tumours and compared with healthy controls (30 cases). Significant difference in enzyme activities were obtained between benign and malignant neoplasms of the breast when compared with each other as well as when compared with healthy controls. Also, there were significant enzyme changes between non-metastatic cases and those with metastasis and when Stage I and Stage II cancers were compared with those in Stage III and Stage IV. No difference in enzyme levels were recorded between pre and post-operative cases and in different types of breast cancers. While ChE was depressed in 80 per cent cases of malignancy breast, serum LDH was raised in 73.3 per cent cases.
对40例乳腺癌患者、25例良性肿瘤患者进行了血清胆碱酯酶（ChE）和乳酸脱氢酶（LDH）活性测定，并与健康对照组（30例）进行比较。乳腺癌的良性和恶性肿瘤之间相互比较以及与健康对照组比较时，酶活性存在显著差异。此外，非转移病例与转移病例之间以及I期和II期癌症与III期和IV期癌症之间酶也有显著变化。术前和术后病例以及不同类型乳腺癌之间酶水平无差异。乳腺癌恶性病例中80%的ChE降低，而73.3%的病例血清LDH升高。
