Buch N A, Ahmed K, Sethi A S
Department of Pediatrics, Government Medical College, Srinagar.
Indian Pediatr. 1991 May;28(5):521-4.
This study is a retrospective analysis of 670 cases of poisoning (including phenothiazine toxicity) admitted to this hospital in the past six years, accounting for 0.9% of all pediatric admissions. Nearly half (45%) of the cases were in the age group of 1-4 years. Medicines and chemicals were the commonest agents (53%), followed by pesticides (15%), kerosene (11.2%), plant poisons (9.4%), food poisoning (3.9%) and corrosives (1.9%). Accidental poisoning was the commonest (70%) followed by iatrogenic (29.6%) and suicidal (0.4%). Overall mortality was 1.8%. Stress is laid on judicious use of phenothiazines as antiemetics and replacing them with drugs of lesser toxicity.
本研究对过去六年里本院收治的670例中毒病例(包括吩噻嗪中毒)进行了回顾性分析,这些病例占儿科住院病例总数的0.9%。近半数(45%)病例年龄在1至4岁。药物和化学品是最常见的中毒因素(53%),其次是农药(15%)、煤油(11.2%)、植物毒素(9.4%)、食物中毒(3.9%)和腐蚀性物质(1.9%)。意外中毒最为常见(70%),其次是医源性中毒(29.6%)和自杀性中毒(0.4%)。总体死亡率为1.8%。强调要谨慎使用吩噻嗪类药物作为止吐剂,并以毒性较小的药物取而代之。