Thomas M, Anandan S, Kuruvilla P J, Singh P R, David S
Department of Pharmacology, Clinical Pharmacology & ADR Monitoring Centre, Vellore, India-632 004.
Adverse Drug React Toxicol Rev. 2000 Dec;19(4):313-7.
This study was conducted to determine the incidence of hospital admissions following acute poisoning, nature of agents involved and change in pattern of poisoning over a 5-year period. Data from hospital records of all admissions to emergency department following acute poisoning collected prospectively were analysed for the period January 1993 to January 1998. A steady increase in deliberate poisoning using pesticides, particularly among young adults, was noted. Kerosene (paraffin) was the commonest poison in children and plant poisons were also common. There were 52 deaths (3.3%) among the 1584 admissions. The majority of deaths were due to pesticides. Poisoning and mortality followed ingestion of readily-available and commonly used agents. Measures to increase public education, counselling and awareness could prevent a number of these admissions.
本研究旨在确定急性中毒后住院治疗的发生率、所涉中毒剂的性质以及5年期间中毒模式的变化。对1993年1月至1998年1月期间前瞻性收集的所有急性中毒后入住急诊科的医院记录数据进行了分析。注意到使用农药蓄意中毒呈稳步上升趋势，尤其是在年轻人中。煤油（石蜡）是儿童中最常见的毒物，植物毒物也很常见。1584例入院病例中有52例死亡（3.3%）。大多数死亡是由农药导致的。中毒和死亡是由于摄入了容易获得和常用的药剂。加强公众教育、咨询和意识的措施可以预防许多此类入院情况。
