[细针穿刺活检在腮腺肿块中的敏感性和特异性]

[Sensitivity and specificity of fine needle aspiration biopsy in parotid masses].

作者信息

Uğuz M Zafer, Onal H Kazim, Eroğlu Ozlem Ozger, Etit Demet

机构信息

Department of Otolaryngology, Izmir Atatürk Training and Research Hospital, Izmir, Turkey.

出版信息

Kulak Burun Bogaz Ihtis Derg. 2007;17(2):96-9.

PMID:17527061

Abstract

OBJECTIVES

We aimed to determine the sensitivity and specificity of fine needle aspiration biopsy (FNAB) in patients with parotid masses.

PATIENTS AND METHODS

The study included 29 patients (15 males, 14 females; mean age 52 years; range 20 to 83 years) who underwent FNAB and parotidectomy for parotid masses. After a detailed history taking, otorhinolaryngologic and systemic examinations were performed. Neck ultrasonography and, when needed, neck computed tomography were used. Superficial parotidectomy was performed in 20 patients and total parotidectomy in nine patients.

RESULTS

The results of FNAB were reported as benign in 21 patients (72.4%), malignant in six patients (20.7%), and suspicious in two patients (6.9%). Postoperative histopathologic diagnoses were reported as benign in 17 patients (58.6%) and malignant in 12 patients (41.4%). The sensitivity and specificity rates for FNAB were 54.6% and 100%, respectively. The most common histopathological diagnosis was pleomorphic adenoma (n=7, 24.1%), followed by mucoepidermoid carcinoma (n=4, 13.8%), and Warthin's tumor (n=3, 10.3%).

CONCLUSION

Preoperative FNAB for parotid masses plays an important role in planning surgery.

摘要

目的

我们旨在确定细针穿刺活检（FNAB）在腮腺肿块患者中的敏感性和特异性。

患者与方法

该研究纳入了29例因腮腺肿块接受FNAB和腮腺切除术的患者（15例男性，14例女性；平均年龄52岁；范围20至83岁）。在详细询问病史后，进行了耳鼻喉科和全身检查。使用了颈部超声检查，必要时还进行了颈部计算机断层扫描。20例患者进行了浅叶腮腺切除术，9例患者进行了全腮腺切除术。

结果

FNAB结果报告为良性的有21例患者（72.4%），恶性的有6例患者（20.7%），可疑的有2例患者（6.9%）。术后组织病理学诊断报告为良性的有17例患者（58.6%），恶性的有12例患者（41.4%）。FNAB的敏感性和特异性分别为54.6%和100%。最常见的组织病理学诊断是多形性腺瘤（n = 7，24.1%），其次是黏液表皮样癌（n = 4，13.8%）和沃辛瘤（n = 3，10.3%）。