Panteliadis C, Tzitiridou M, Pavlidou E, Hagel C, Covanis A, Jacobi G
Abt. für Pädiatrie und Neuropädiatrie, Universitätskinderklinik, Thessaloniki.
Nervenarzt. 2007 Oct;78(10):1188-94. doi: 10.1007/s00115-007-2296-y.
Congenital hemiplegia, defined as unilateral motor disability, is the hemiplegic type of cerebral palsy. The prevalence of congenital hemiplegia is estimated to be about 0.41-0.79/1000 live births. We examined 223 children (122 boys and 101 girls) suffering from congenital hemiplegia at the age of 3 months to 12 years. Mild hemiplegia was found in 31%, a moderate form in 48%, and a severe form in 21%. The upper limb was affected in more than half of the patients, only the lower extremity in one third, and both upper and lower limbs in 20%. Electroencephalographic abnormalities were found in 75.8% of the patients. The most frequent type of epilepsy was complex partial seizures (33%). Severity of the motor handicap, grade of EEG abnormalities, and the prevalence of epilepsy showed a significant correlation. The magnitude of the lesions in neuroimaging directly correlated with these three clinical variables, particularly in children with cortical and subcortical defects (84.2%). Strabismus was the most common visual impairment (17%), while hearing impairment was found in 8% of the patients. Of them, 38.3% showed no cognitive deficits, while those with severe congenital hemiplegia were found to have a lower intelligence quotient.
先天性偏瘫被定义为单侧运动功能障碍,是脑瘫的偏瘫类型。据估计,先天性偏瘫的患病率约为每1000例活产中有0.41 - 0.79例。我们对223名年龄在3个月至12岁之间的先天性偏瘫儿童进行了检查(122名男孩和101名女孩)。发现轻度偏瘫的患儿占31%,中度偏瘫的占48%,重度偏瘫的占21%。超过一半的患者上肢受到影响,三分之一的患者仅下肢受到影响,20%的患者上下肢均受到影响。75.8%的患者存在脑电图异常。最常见的癫痫类型是复杂部分性发作(33%)。运动障碍的严重程度、脑电图异常程度和癫痫患病率之间存在显著相关性。神经影像学检查中病变的严重程度与这三个临床变量直接相关,特别是在伴有皮质和皮质下缺陷的儿童中(84.2%)。斜视是最常见的视力障碍(17%),8%的患者存在听力障碍。其中,38.3%的患者没有认知缺陷,而重度先天性偏瘫患者的智商较低。