Grand Sylvie D, Kremer Stéphane, Tropres Irène M, Hoffmann Dominique M, Chabardes Stephan J, Lefournier Virginie, Berger François R, Pasteris Caroline, Krainik Alexandre, Pasquier Basile M, Peoch Michel, Le Bas Jean François
Neuroradiology, Hôpital Michallon, Grenoble, France.
Neuroradiology. 2007 Jul;49(7):545-50. doi: 10.1007/s00234-006-0204-y. Epub 2007 May 26.
To present the imaging and perfusion data obtained in nine patients with pilocytic astrocytomas (PA) and to discuss the original functional issues of this technique.
Nine patients with pathologically proven PA underwent conventional and perfusion MR imaging. Various areas of relative cerebral blood volume (rCBV) within the tumors were obtained. The maximum rCBV ratios were identified and considered as representative of the tumor. The results were compared with the pathological findings.
In all patients, rCBV was <1.5 (mean 1) and the signal intensity curve overshot the baseline.
PA tend to have low rCBV values and a first-pass curve that crosses the baseline. These characteristics may be explained by the histological profile of the tumoral vascularity and are of relevance in the identification of these rare tumors.
展示9例毛细胞型星形细胞瘤（PA）患者的成像和灌注数据，并讨论该技术的原始功能问题。
9例经病理证实为PA的患者接受了传统和灌注磁共振成像。获取肿瘤内相对脑血容量（rCBV）的各个区域。确定最大rCBV比值并将其视为肿瘤的代表。将结果与病理结果进行比较。
所有患者的rCBV均<1.5（平均1），且信号强度曲线超过基线。
PA往往具有较低的rCBV值和穿过基线的首过曲线。这些特征可能由肿瘤血管的组织学特征来解释，并且在识别这些罕见肿瘤方面具有相关性。
