Margaros Ioannis, Vassilikogiannakis Georgios
Department of Chemistry, University of Crete, Vasilika Vouton, 71003 Iraklion, Crete, Greece.
J Org Chem. 2007 Jun 22;72(13):4826-31. doi: 10.1021/jo070527v. Epub 2007 May 27.
Short and efficient syntheses of coronarin E (4) and chinensines A-E (5-9) have been accomplished. The use of two different types of reaction of singlet oxygen ((1)O(2)) lies at the heart of the synthetic strategy. The syntheses have facilitated the clarification of certain previously unknown, or unconfirmed, stereochemical details (the relativity stereochemistries of chinensines D and E and the absolute stereochemistries for all the synthesized family members).
已完成了冠菌素E（4）和中国菌素A - E（5 - 9）的简短高效合成。单线态氧（(1)O(2)）的两种不同类型反应的运用是合成策略的核心。这些合成工作有助于阐明某些先前未知或未得到确认的立体化学细节（中国菌素D和E的相对立体化学以及所有合成家族成员的绝对立体化学）。
