在精神病院中的处女的生殖器人乳头瘤病毒感染。
Genital human papilloma virus infection in mentally-institutionalized virgins.
作者信息
Shimada Takako, Miyashita Masako, Miura Shoko, Nakayama Daisuke, Miura Kiyonori, Fukuda Masafumi, Masuzaki Hideaki
机构信息
Department of Obstetrics and Gynecology, Nagasaki University Graduated School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, and Yasunaga Obstetrics and Gynecology Hospital, Isahaya, Japan.
出版信息
Gynecol Oncol. 2007 Sep;106(3):488-9. doi: 10.1016/j.ygyno.2007.04.018. Epub 2007 May 25.
OBJECTIVE
Human papilloma virus (HPV) can cause cervical cancer. Risk factors for HPV infection are primarily related to sexual behavior. We determined the prevalence of HPV infection and abnormal cervical cytology in institutionalized women with no previous sexual experience.
METHODS
The study subjects were 251 patients who sought screening for cervical cancer (45.9+/-9.4 years, mean+/-S.D., range, 14 to 66). They were institutionalized for psychosomatic disorders since childhood, and had no previous sexual experience. In addition to screening for cervical cancer, specimens for HPV testing were collected.
RESULTS
No women who were positive for HPV DNA was detected, though 251 women without sexual experiences were screened by the hybrid capture 2 test including 26 types of HPV-DNA.
CONCLUSION
Transmission through means other than sexual intercourse may not exist because we could not detect HPV DNA in 251 women with no previous sexual experience.
目的
人乳头瘤病毒（HPV）可引发宫颈癌。HPV感染的风险因素主要与性行为相关。我们测定了既往无性经历的机构收容女性中HPV感染及宫颈细胞学异常的患病率。
方法
研究对象为251例寻求宫颈癌筛查的患者（平均年龄45.9±9.4岁，标准差，范围14至66岁）。她们自幼因身心疾病被收容，既往无性经历。除宫颈癌筛查外，还采集了HPV检测标本。
结果
尽管通过杂交捕获2法检测了251例无性经历女性的26种HPV-DNA，但未检测到HPV DNA阳性的女性。
结论
由于在251例既往无性经历的女性中未检测到HPV DNA，因此可能不存在通过性行为以外途径传播的情况。
Zotero 插件