一项关于三叉神经节刺激治疗三叉神经神经性疼痛的为期12个月的前瞻性研究。
A 12-month prospective study of gasserian ganglion stimulation for trigeminal neuropathic pain.
作者信息
Machado A, Ogrin M, Rosenow J M, Henderson J M
机构信息
Center for Neurological Restoration, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
出版信息
Stereotact Funct Neurosurg. 2007;85(5):216-24. doi: 10.1159/000103260. Epub 2007 May 25.
AIMS
Trigeminal neuropathic pain is a broad diagnostic category that includes pain of several etiologies and excludes trigeminal neuralgia. The authors report a prospective series of percutaneous gasserian ganglion stimulation for trigeminal neuropathic pain.
METHODS
Patients who experienced >50% reduction in pain from a 7- to 10-day trial period underwent permanent implantation and were prospectively followed.
RESULTS
Eight of 10 trialed patients received a permanent implant. At the 12-month follow-up, 2 patients had been explanted and 1 was lost to follow-up. Three (all working at that the time) continued to experience >50% improvement in pain.
DISCUSSION
The results in this series were variable but 3 patients showed long-term improvements. Patients who continued to work responded better to treatment.
目的
三叉神经性疼痛是一个宽泛的诊断类别，包括多种病因引起的疼痛，不包括三叉神经痛。作者报告了一系列针对三叉神经性疼痛的经皮半月神经节刺激术的前瞻性研究。
方法
在为期7至10天的试验期内疼痛减轻超过50%的患者接受永久性植入，并进行前瞻性随访。
结果
10名受试患者中有8名接受了永久性植入。在12个月的随访中，2名患者的植入装置已被取出，1名患者失访。3名患者（当时均在工作）的疼痛持续改善超过50%。
讨论
本系列研究结果存在差异，但3名患者显示出长期改善。继续工作的患者对治疗反应更好。
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