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[一例肾盂癌合并非酮症高渗性糖尿病昏迷致腰大肌脓肿的病例]

[A case of psoas abscess due to renal pelvic carcinoma complicated with non-ketotic hyperosmolar diabetic coma].

作者信息

Miyata Y, Fujii Y, Kitade K, Hara M

机构信息

Department of Internal Medicine, Ehime Prefectual Central Hospital.

出版信息

Nihon Ronen Igakkai Zasshi. 1991 Sep;28(5):688-92. doi: 10.3143/geriatrics.28.688.

Abstract

A 85-year-old man was admitted to our hospital because of semicomatous status. Laboratory data on admission showed elevation of blood sugar (823 mg/dl) and serum osmotic pressure (345 mOsm/l), but ketonuria was not detected. Non-ketotic hyperosmolar diabetic coma was diagnosed. The insulin infusion and physiological saline improved the blood sugar level and consciousness within a day. The abdominal ultrasound examination revealed an abscess in the left kidney and right psoas muscle. The same findings were seen by abdominal computed tomography but the possibility of malignant neoplasm of the left kidney could not be ruled out because of a swelling of the left adrenal gland. Pain associated with psoas abscess and low grade fever were observed. Because of his poor general condition, drainage of the abscess was not performed and conservative therapy using antibiotics was administered. Without any improvement of the abscess, he died due to general deterioration four months later. Autopsy findings showed carcinoma of the left renal pelvis and metastasis to the right psoas muscle, left adrenal gland, liver, bilateral lungs and lymph modes. Psoas abscess is a relatively uncommon disease, especially in elderly patients. The etiology of the disease is divided into primary and secondary causes. Most secondary psoas abscess cases are caused by intestinal diseases, and Crohn's disease has been related to the highest incidence. A few cases of psoas abscess caused by colorectal carcinoma have been reported. Ultrasound and computed tomography are useful in diagnosing this disease and drainage of an abscess is necessary for therapy and proving the cause. Cancer metastasis should considered in differential diagnoses, when psoas abscess is seen in elderly patients.

摘要

一名85岁男性因半昏迷状态入院。入院时实验室检查数据显示血糖升高(823mg/dl)和血清渗透压升高(345mOsm/l),但未检测到酮尿。诊断为非酮症高渗性糖尿病昏迷。胰岛素输注和生理盐水在一天内改善了血糖水平和意识。腹部超声检查显示左肾和右腰大肌有脓肿。腹部计算机断层扫描也有同样的发现,但由于左肾上腺肿大,不能排除左肾恶性肿瘤的可能性。观察到与腰大肌脓肿相关的疼痛和低热。由于他的一般状况较差,未进行脓肿引流,而是给予抗生素保守治疗。脓肿没有任何改善,四个月后他因全身状况恶化而死亡。尸检结果显示左肾盂癌并转移至右腰大肌、左肾上腺、肝脏、双侧肺和淋巴结。腰大肌脓肿是一种相对罕见的疾病,尤其是在老年患者中。该病的病因分为原发性和继发性。大多数继发性腰大肌脓肿病例由肠道疾病引起,其中克罗恩病的发病率最高。已有少数由结直肠癌引起腰大肌脓肿的病例报道。超声和计算机断层扫描对诊断该病很有用,脓肿引流对于治疗和查明病因是必要的。当老年患者出现腰大肌脓肿时,鉴别诊断应考虑癌症转移。

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