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关于结局和基线风险的医院评估——经皮冠状动脉介入治疗的应用

Evaluation of hospitals regarding outcomes and baseline risk -- an application to percutaneous coronary intervention.

作者信息

Hochadel Matthias, Schneider Steffen, Gottwik Martin, Zahn Ralf, Zeymer Uwe, Senges Jochen

机构信息

Institut für Herzinfarktforschung, Bremserstrasse 79, 67063 Ludwigshafen am Rhein, Germany.

出版信息

Clin Res Cardiol. 2007 Jul;96(7):502-7. doi: 10.1007/s00392-007-0529-5. Epub 2007 Jun 4.

Abstract

UNLABELLED

Monitoring of hospital performance is increasingly used in the process of improving the quality of health care. Various approaches to quality assessment and publication of the results are discussed. Therefore, a method acceptable for clinicians in the hospitals is urgently needed. As the case mix of the patients differs considerably across hospitals, any assessment based on outcome measures has to be adjusted for the patients' risk profiles. We use a method of calculation and presentation that relates the observed complication rate of one centre to the mean rate that would be expected for similar patients in the other centres. We argue that this procedure might especially meet the demands of clinicians in the centres. Data from 44 hospitals in the German Cypher Stent Registry are used to exemplify the proposed procedure.

RESULTS

A large variation in the cumulative incidence of MACE within 6 months (range 0-12.2%) as well as in the prevalence of selected risk factors was observed across hospitals. Using a logistic prediction model, the differences in risk profiles of the patient populations in the centres resulted in a wide range of expected MACE rates (2.55-5.44%). The outcome of seven centres differed significantly from the expectation.

CONCLUSION

In comparisons of the outcome quality of hospitals, adjustment for the patients' baseline risk by an appropriate method is indispensable.

摘要

未标注

在提高医疗质量的过程中,医院绩效监测的应用越来越广泛。人们讨论了各种质量评估方法和结果发布方式。因此,迫切需要一种医院临床医生能够接受的方法。由于不同医院患者的病例组合差异很大,任何基于结果指标的评估都必须根据患者的风险状况进行调整。我们使用一种计算和呈现方法,将一个中心观察到的并发症发生率与其他中心类似患者预期的平均发生率相关联。我们认为,这一程序可能特别符合各中心临床医生的需求。来自德国西罗莫司洗脱支架注册研究中44家医院的数据用于举例说明所提议的程序。

结果

各医院6个月内心血管不良事件(MACE)累积发生率(范围为0 - 12.2%)以及选定风险因素的患病率差异很大。使用逻辑预测模型,各中心患者群体的风险状况差异导致预期MACE发生率范围很广(2.55 - 5.44%)。七个中心的结果与预期有显著差异。

结论

在比较医院的结果质量时,通过适当方法对患者基线风险进行调整是必不可少的。

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