Yamamoto M, Ukita H, Akiyama Y, Nishimura M, Kishi F, Kawakami Y
First Department of Medicine, School of Medicine, Hokkaido University, Sapporo.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Oct;29(10):1339-43.
A 76-year-old man, whose carotid bodies had been resected for treatment of bronchial asthma 40 years previously was admitted for evaluation of abnormal arterial blood gases and exertional dyspnea. The case was diagnosed clinically as chronic pulmonary emphysema. His peripheral chemoreceptor function, estimated by hypoxic ventilatory and P0.1 response tests and withdrawal test was non-functioning. His PaCO2 value tended to rise over 50 Torr either after light exercise or during airway infection, though it was normal at rest. In addition his dyspnea had continued for 40 years in spite of carotid body resection. It was concluded that the effect of carotid body resection lasts more than 40 years and it does not have a good effect on COPD.
一名76岁男性，40年前因治疗支气管哮喘切除了颈动脉体，现因动脉血气异常和劳力性呼吸困难入院评估。临床诊断为慢性肺气肿。通过低氧通气、P0.1反应试验和撤药试验评估，其外周化学感受器功能丧失。尽管静息时其动脉血二氧化碳分压（PaCO2）值正常，但轻度运动后或气道感染期间该值往往会升至50托以上。此外，尽管切除了颈动脉体，其呼吸困难仍持续了40年。结论是，颈动脉体切除的影响持续超过40年，对慢性阻塞性肺疾病（COPD）没有良好效果。
