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[原发性结节性肺淀粉样变性1例的免疫组织化学及电镜研究]

[Immunohistochemical and electromicroscopic study of a case of primary nodular pulmonary amyloidosis].

作者信息

Amishima M, Tsuneta Y, Iwata I, Makino H, Nishiura Y, Kawai T, Maguri M

机构信息

Department of Respiratory Medicine, Kohnan Hospital, Sapporo, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Aug;29(8):1075-8.

PMID:1753526
Abstract

A 41-year-old man was hospitalized for further evaluation of an abnormal chest films which revealed a nodular shadow in the right middle lung field, which remarkably enlarged during one year. As no diagnostic procedures ruled out lung carcinoma of right S6, a right lower lobectomy was performed. Pathologically the nodules were composed of amorphous and eosionphilic materials which were diagnosed as amyloid by Congo-red stain and electron microscopic examination. Since there were no deposits in other organs and there was no abnormality of serologic and urinary protein analysis, a diagnosis of primary nodular pulmonary amyloidosis was established.

摘要

一名41岁男性因胸部X线片异常入院进一步评估,X线片显示右肺中叶有一结节状阴影,该阴影在一年内明显增大。由于没有诊断方法能够排除右肺S6段肺癌,遂行右下肺叶切除术。病理检查显示结节由无定形嗜酸性物质组成,经刚果红染色和电子显微镜检查诊断为淀粉样变。由于其他器官没有沉积物,血清学和尿蛋白分析也无异常,故诊断为原发性结节性肺淀粉样变。

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