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急性心脏事件后12个月内女性焦虑和抑郁的轨迹及预测因素。

Trajectories and predictors of anxiety and depression in women during the 12 months following an acute cardiac event.

作者信息

Murphy Barbara M, Elliott Peter C, Worcester Marian U C, Higgins Rosemary O, Le Grande Michael R, Roberts Susan B, Goble Alan J

机构信息

Heart Research Centre, Melbourne, Victoria, Australia.

出版信息

Br J Health Psychol. 2008 Feb;13(Pt 1):135-53. doi: 10.1348/135910707X173312.

Abstract

OBJECTIVES

Many previous investigations of the recovery of emotional well-being, particularly the resolution of depression, following an acute cardiac event assume that all patients follow a similar, linear trajectory. However, it is possible that there are different groups of patients who follow different trajectories. This study tested for multiple trajectories of anxiety and depression and identified the characteristics of patients most at risk for persistent or worsening anxiety and depression in the 12 months following their cardiac event.

METHOD

A consecutive sample of 226 women was interviewed following either acute myocardial infarction (AMI) or coronary artery bypass graft surgery (CABGS). The Hospital Anxiety and Depression Scale were administered on four occasions over 12 months. Growth curve and growth mixture modelling were used to identify trajectories of change and univariate tests were employed to establish predictors of each trajectory.

RESULTS

Most women began with relatively low levels of anxiety and/or depression that improved over the 12 month period (84% women showed this trajectory for anxiety, 89% for depression). A smaller group began with relatively high levels of anxiety and/or depression that worsened over time (16% for anxiety, 11% for depression). Patients in the latter group were more likely to report high levels of loneliness, have a first language other than English, perceive their cardiac disease as more severe (anxiety group only) and have diabetes (depression group only). Trajectories were non-linear, with most change occurring in the initial 2-month period.

CONCLUSION

Growth modelling techniques highlight that change in anxiety and depression following an acute event follows neither a single nor linear trajectory. Most women showed early resolution of anxiety and depression following their event, indicative of a normal bereavement or adjustment response. A minority of women reported worsening anxiety and/or depression in the year following their cardiac event, particularly those who lacked social support or were from non-English speaking backgrounds. Intervention studies to explore support options for these women are warranted, both prior to and following their event.

摘要

目的

以往许多关于急性心脏事件后情绪健康恢复,尤其是抑郁症缓解情况的研究都假定所有患者都遵循相似的线性轨迹。然而,有可能存在不同组的患者遵循不同的轨迹。本研究测试了焦虑和抑郁的多种轨迹,并确定了在心脏事件发生后的12个月内持续存在或焦虑和抑郁加重风险最高的患者特征。

方法

对226名女性进行连续抽样,她们均经历了急性心肌梗死(AMI)或冠状动脉搭桥手术(CABGS)。在12个月内分四次使用医院焦虑抑郁量表进行评估。采用生长曲线和生长混合模型来识别变化轨迹,并使用单变量检验来确定每个轨迹的预测因素。

结果

大多数女性开始时焦虑和/或抑郁水平相对较低,在12个月期间有所改善(84%的女性焦虑呈此轨迹,89%的女性抑郁呈此轨迹)。一小部分女性开始时焦虑和/或抑郁水平相对较高,且随时间恶化(焦虑为16%,抑郁为11%)。后一组患者更有可能报告高度孤独感、母语不是英语、认为自己的心脏病更严重(仅焦虑组)以及患有糖尿病(仅抑郁组)。轨迹是非线性的,大部分变化发生在最初的2个月内。

结论

生长模型技术突出表明,急性事件后焦虑和抑郁的变化既不遵循单一轨迹也不遵循线性轨迹。大多数女性在事件后焦虑和抑郁早期得到缓解,这表明是正常的丧亲或调整反应。少数女性在心脏事件后的一年内报告焦虑和/或抑郁加重,尤其是那些缺乏社会支持或来自非英语背景的女性。有必要开展干预研究,在这些女性事件发生之前和之后探索支持方案。

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