Shinohara A, Fukuda K, Maeda K, Ogushi F, Sone S, Ogura T, Shinomiya S
Third Department of Internal Medicine, Tokushima University School of Medicine.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Sep;29(9):1211-5.
A 63-year-old female, with a chief complaint of right chest pain was referred to our hospital because of an abnormal right chest wall shadow on chest X-ray. A rib tumor was suspected based on her chest CT scan. Percutaneous needle biopsy yielded a diagnosis of well-differentiated adenocarcinoma. As metastatic rib tumor was suspected, the primary tumor was sought for. A thyroid gland nodule was recognized by ultrasonography, and the cytological diagnosis was class V. Immunohistological demonstration of the thyroglobulin studies of the rib tumor tissue revealed papillary and trabecular patterns of cell arrangement and the presence of thyroglobulin existence. Definitive diagnosis of metastatic rib tumor from thyroid cancer was established. Immunohistological examination is useful to confirm the diagnosis of metastatic cancer of thyroid origin.
一名63岁女性,因主诉右胸痛,胸部X线显示右胸壁阴影异常而转诊至我院。根据胸部CT扫描怀疑为肋骨肿瘤。经皮针吸活检诊断为高分化腺癌。由于怀疑是转移性肋骨肿瘤,遂寻找原发肿瘤。超声检查发现甲状腺有一个结节,细胞学诊断为V级。对肋骨肿瘤组织进行甲状腺球蛋白免疫组织学检测,显示细胞排列呈乳头状和小梁状,且存在甲状腺球蛋白。确诊为甲状腺癌转移性肋骨肿瘤。免疫组织学检查有助于确诊甲状腺源性转移性癌。