Sinha S, Munikrishnan V, Montgomery J, Mitchell S J
Department of General Surgery, Torbay Hospital, Torquay, UK.
Ann R Coll Surg Engl. 2007 May;89(4):374-8. doi: 10.1308/003588407X183337.
Laparoscopic cholecystectomy has revolutionised the management of symptomatic gallstones and is increasingly performed as a day-case procedure. The aim of this study was to assess the impact of opioid patient-controlled analgesia (PCA) on elective laparoscopic cholecystectomy.
In a prospective, non-randomised, observational study, 76 consecutive patients who underwent elective in-patient laparoscopic cholecystectomy were reviewed. Six patients with complicated gall stone disease and four patients who converted from laparoscopic to an open operation were excluded.
Of the 66 remaining in the study group, 25 patients received morphine-PCA and, of these, 9 were fit for discharge. In contrast, 41 patients did not receive PCA and, of these, 27 were fit for discharge (P < 0.05). Median Aldrete score in the PCA group was 16 and in the non-PCA group 18 (P < 0.05). Postoperative nausea and vomiting were more common in patients receiving a morphine-based PCA and with in those with higher anti-emetic requirement (10/25 in PCA and 7/41 non-PCA groups; P < 0.05).
Routine postoperative opioid PCA prolongs the recovery and in-patient stay following elective laparoscopic cholecystectomy. Its role in postoperative pain management in routine laparoscopic cholecystectomy should be questioned.
腹腔镜胆囊切除术彻底改变了有症状胆结石的治疗方式,且越来越多地作为日间手术进行。本研究的目的是评估阿片类药物患者自控镇痛(PCA)对择期腹腔镜胆囊切除术的影响。
在一项前瞻性、非随机、观察性研究中,对76例连续接受择期住院腹腔镜胆囊切除术的患者进行了评估。排除6例患有复杂胆结石疾病的患者和4例由腹腔镜手术转为开放手术的患者。
在研究组剩余的66例患者中,25例接受了吗啡PCA,其中9例适合出院。相比之下,41例未接受PCA的患者中,27例适合出院(P<0.05)。PCA组的Aldrete评分中位数为16,非PCA组为18(P<0.05)。接受基于吗啡的PCA的患者以及抗呕吐需求较高的患者术后恶心和呕吐更为常见(PCA组10/25,非PCA组7/41;P<0.05)。
择期腹腔镜胆囊切除术后常规使用阿片类药物PCA会延长恢复时间和住院时间。其在常规腹腔镜胆囊切除术术后疼痛管理中的作用值得质疑。