van Dalen Jorn A, Vogel Wouter V, Corstens Frans H M, Oyen Wim J G
Radboud University Medical Centre Nijmegen, Department of Nuclear Medicine, Nijmegen, The Netherlands.
Cancer Imaging. 2007 May 28;7(1):77-83. doi: 10.1102/1470-7330.2007.0014.
Multi-modality imaging is rapidly becoming an essential tool in oncology. Clinically, the best example of multimodality imaging is seen in the rapid evolution of hybrid positron emission tomography (PET)/computed tomography (CT) and single positron emission computed tomography (SPECT)/CT scanners. However, use of multi-modality imaging is prone to artefacts and pitfalls. Important artefacts that may lead to clinical misinterpretation result from the use of CT data to correct for attenuation and the existence of mismatches between the fused images, for example due to respiratory movement. Furthermore, for institutions who proceed from a standalone PET to a hybrid PET-CT, there is an issue of interchangeability between these systems, especially for quantitative studies. Another issue is visualisation: hospital PACS is not sufficiently capable of adequately viewing integrated images. This article reviews and illustrates the most common artefacts and pitfalls that can be encountered in multi-modality nuclear medicine imaging. For correct management of oncological patients it is essential to be able to detect and correctly interpret these artefacts and pitfalls. Therefore, solutions and recommendations to these problems are provided.
多模态成像正迅速成为肿瘤学领域的一项重要工具。在临床上，多模态成像的最佳范例体现在正电子发射断层扫描（PET）/计算机断层扫描（CT）和单光子发射计算机断层扫描（SPECT）/CT扫描仪的快速发展上。然而，多模态成像的使用容易出现伪影和陷阱。可能导致临床误判重要伪影，是由于使用CT数据进行衰减校正以及融合图像之间存在不匹配，例如由于呼吸运动。此外，对于从独立PET过渡到PET-CT混合系统的机构来说，这些系统之间存在互换性问题，特别是在定量研究方面。另一个问题是图像显示：医院的图像存档与通信系统（PACS）没有足够能力充分查看融合图像。本文回顾并举例说明了多模态核医学成像中可能遇到的最常见伪影和陷阱。对于肿瘤患者的正确管理，能够检测并正确解读这些伪影和陷阱至关重要。因此，本文还提供了针对这些问题的解决方案和建议。
