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脊髓损伤中神经源性膀胱尿动力学研究的可重复性

The reproducibility of urodynamic studies of neurogenic bladders in spinal cord injury.

作者信息

Ho C H, Linsenmeyer T A, Millis S R

机构信息

Kessler Institute for Rehabilitation, 1199 Pleasant Valley Way, West Orange, NJ 07052, USA.

出版信息

J Spinal Cord Med. 2000 Winter;23(4):276-83. doi: 10.1080/10790268.2000.11753537.

Abstract

OBJECTIVE

To evaluate the reproducibility (test-retest reliability) of urodynamic studies in neurogenic bladders of subjects with spinal cord injuries (SCI).

DESIGN

Retrospective case series.

SETTING

Urology department of a major rehabilitation center.

SUBJECTS

Fifty individuals with SCI who had urodynamic studies performed from February 2000 to April 2000.

MAIN OUTCOME MEASURES

Two trials (Time 1 and Time 2) of urodynamic studies done 5 minutes apart, with the following collected: bladder volume at first sensation, maximum cystometric capacity, presence of uninhibited contractions, opening pressure, maximum detrusor pressure, duration of bladder contraction, volume voided, and post-void residual (PVR) volume. The corresponding data were then compared. Statistical analysis was performed using the Lin's concordance correlation coefficient and kappa.

RESULTS

Analysis of the data showed statistically significant levels of agreement between Time 1 and Time 2 with regard to the various corresponding parameters for both the filling and voiding phases. For 3 of the most important parameters-the opening pressure, maximum detrusor pressure, and duration of contraction-the Lin's concordance correlation coefficient (r(c)) was .86 (95% CI, .78-.95; p < .0005), .91 (95% CI, .86-.96; p < .0005), and .97 (95% CI, .95-.99, p < .0005), respectively.

CONCLUSION

The study demonstrates good short-term intrasubject reproducibility of urodynamic studies in individuals with SCI.

摘要

目的

评估脊髓损伤(SCI)患者神经源性膀胱尿动力学研究的可重复性(重测信度)。

设计

回顾性病例系列研究。

地点

一家大型康复中心的泌尿外科。

研究对象

2000年2月至2000年4月期间接受尿动力学研究的50例SCI患者。

主要观察指标

相隔5分钟进行两次尿动力学试验(时间1和时间2),收集以下数据:首次感觉时的膀胱容量、最大膀胱测压容量、有无无抑制性收缩、开放压、最大逼尿肌压力、膀胱收缩持续时间、排尿量和残余尿量(PVR)。然后对相应数据进行比较。使用林氏一致性相关系数和kappa进行统计分析。

结果

数据分析显示,在充盈期和排尿期的各项相应参数方面,时间1和时间2之间存在统计学上显著的一致性水平。对于3个最重要的参数——开放压、最大逼尿肌压力和收缩持续时间——林氏一致性相关系数(r(c))分别为0.86(95%CI,0.78 - 0.95;p < 0.0005)、0.91(95%CI,0.86 - 0.96;p < 0.0005)和0.97(95%CI,0.95 - 0.99,p < 0.0005)。

结论

该研究表明SCI患者尿动力学研究具有良好的短期个体内可重复性。

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