Hitani Kouichirou, Yamamoto Teiko, Sato Yukihiro
Department of Ophthalmology, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, Chiba 285-8741, Japan.
Nippon Ganka Gakkai Zasshi. 2007 May;111(5):401-6.
To investigate the long-term results of grid pattern photocoagulation for diffuse diabetic macular edema.
In 45 cases, 56 eyes foveal thickness and visual outcome were observed 12 months or more after grid pattern photocoagulation.
Compared with preoperative values, average foveal thickness decreased significantly during the initial 3 postoperative months and this reduction was maintained through 30 postoperative months. Foveal thickness was reduced by more than 20% in 66% of eyes. The final logarithm of the minimum angle of resolution (logMAR) visual acuity improved 0.2 or more in 41% of eyes. There was a significant correlation between preoperative and postoperative visual acuity. A final visual acuity of 0.5 or better was obtained in 80% of eyes with a preoperative visual acuity of 0.4 or better. There were no eyes with visual loss due to atrophic creep in this study.
Grid pattern photocoagulation for diffuse diabetic macular edema showed long-term effectiveness in reducing foveal thickness postoperatively. It will be possible to achieve a final visual acuity of 0.5 or better in a high percentage of cases, if grid pattern photocoagulation is performed for those with relatively good visual acuity. The foveal thickness measurement was useful for quantitative evaluation of photocoagulation for diabetic macular edema.
探讨格栅样光凝治疗糖尿病性黄斑弥漫性水肿的长期效果。
45例患者共56只眼，在格栅样光凝术后12个月或更长时间观察黄斑中心凹厚度及视力情况。
与术前相比，术后最初3个月平均黄斑中心凹厚度显著降低，且这种降低持续至术后30个月。66%的患眼中黄斑中心凹厚度降低超过20%。41%的患眼最小分辨角对数视力（logMAR）最终提高0.2或更多。术前和术后视力之间存在显著相关性。术前视力为0.4或更好的患眼中，80%最终视力达到0.5或更好。本研究中没有因萎缩性进展导致视力丧失的患眼。
格栅样光凝治疗糖尿病性黄斑弥漫性水肿在术后降低黄斑中心凹厚度方面显示出长期有效性。对于视力相对较好的患者进行格栅样光凝，在高比例病例中有可能达到最终视力0.5或更好。黄斑中心凹厚度测量有助于对糖尿病性黄斑水肿光凝效果进行定量评估。
