压片涂片中亚室管膜下巨细胞星形细胞瘤的细胞学特征：与肥胖型星形细胞瘤和巨细胞胶质母细胞瘤的形态计量学比较
Cytologic characteristics of subependymal giant cell astrocytoma in squash smears: morphometric comparisons with gemistocytic astrocytoma and giant cell glioblastoma.
作者信息
Kim Se Hoon, Lee Kwang-Gil, Kim Tai Seung
机构信息
Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea.
出版信息
Acta Cytol. 2007 May-Jun;51(3):375-9. doi: 10.1159/000325750.
OBJECTIVE
To evaluate the squash smear features of subependymal giant cell astrocytoma (SEGA) in comparison with gemistocytic astrocytoma and giant cell glioblastoma.
STUDY DESIGN
We compared the squash smear features of 3 cases of SEGA, 9 cases of gemistocytic astrocytoma and 3 cases of giant cell glioblastoma with the morphometric findings.
RESULTS
SEGA had, on average, a 15.84 +/- 5.03-microm nucleus, 33.22 +/- 12.05-microm cytoplasm and 0.50 +/- 0.12 nuclear/cytoplasmic ratio in squash smears. In addition, SEGA showed hairlike processes distributed along the squash direction like strap cells. While the gemistocytic astrocytoma had several tumor cells showing a vertically located nucleus, the tumor cells of SEGA showed nuclei oriented mainly in parallel.
CONCLUSION
These squash cytologic features of SEGA can be very helpful in the differential diagnosis by excluding mimics.
目的
评估室管膜下巨细胞星形细胞瘤（SEGA）与肥胖型星形细胞瘤和巨细胞胶质母细胞瘤相比的压片涂片特征。
研究设计
我们将3例SEGA、9例肥胖型星形细胞瘤和3例巨细胞胶质母细胞瘤的压片涂片特征与形态学测量结果进行了比较。
结果
在压片涂片中，SEGA平均有一个15.84±5.03微米的细胞核、33.22±12.05微米的细胞质以及0.50±0.12的核质比。此外，SEGA显示出沿压片方向分布的毛发样突起，类似束状细胞。虽然肥胖型星形细胞瘤有几个肿瘤细胞显示细胞核垂直定位，但SEGA的肿瘤细胞显示细胞核主要平行排列。
结论
SEGA的这些压片细胞学特征在排除模仿病变进行鉴别诊断时非常有帮助。
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