Rossa V, Sundmacher R, Schmitt-Gräff A, Heering P
Univ.-Augenklinik Düsseldorf.
Klin Monbl Augenheilkd. 1991 Sep;199(3):165-9. doi: 10.1055/s-2008-1046065.
A severe, spontaneously acquired, bilateral, sight threatening Ulcus rodens Mooren of a 31 years old type I diabetic will be demonstrated in its clinical course. An improvement was achieved by a systemic immunomodulating therapy with Ciclosporin A that had to be tapered after 3 weeks due to severe side effects. The exclusive local therapy showed no effect at all. Later, the patient underwent a penetrating keratoplasty and extracapsular cataract extraction of both eyes under systemic Ciclosporin A therapy. The graft of the left eye failed due to a foudroyant bacterial infection whereas the keratoplasty of the right eye was successful up to this day despite of various complications.
将展示一名31岁I型糖尿病患者严重的、自发获得的双侧威胁视力的莫伦溃疡性睑缘炎的临床病程。通过环孢素A进行全身免疫调节治疗取得了改善，但由于严重的副作用，3周后不得不逐渐减少剂量。单纯局部治疗完全无效。后来，患者在全身使用环孢素A治疗下接受了双眼穿透性角膜移植术和白内障囊外摘除术。左眼的移植物因暴发性细菌感染而失败，而右眼的角膜移植术尽管有各种并发症，但至今仍成功。
