来自兜兰属植物的芪类化合物

Stilbenes from the Orchid Phragmipedium sp.

作者信息

Garo Eliane, Hu Jin-Feng, Goering Matt, Hough Grayson, O'Neil-Johnson Mark, Eldridge Gary

机构信息

Lead Discovery and Rapid Structure Elucidation Group, Sequoia Sciences Inc., 1912 Innerbelt Business Center Drive, Saint Louis, Missouri 63114, USA.

出版信息

J Nat Prod. 2007 Jun;70(6):968-73. doi: 10.1021/np070014j. Epub 2007 May 31.

DOI:10.1021/np070014j

PMID:17536858

Abstract

Three species of Phragmipedium (Orchidaceae), P. calurum, P. longifolium, and P. hybrid (var. Sorcerer's Apprentice), were analyzed by high-throughput isolation. A total of 12 new (1-4, 6-10, 12, 14, 16) and five known compounds (5, 11, 13, 15, 17) were isolated from these orchids. Compounds 1-8 are stilbenes substituted with one or two 4-hydroxybenzyl moieties. This type of substitution on stilbenes is unusual and has been reported only twice. The structure elucidation was based on spectroscopic analysis.

摘要

对三种兜兰属（兰科）植物，即卡卢卢兜兰、长叶兜兰和杂交兜兰（品种“魔法师的学徒”）进行了高通量分离分析。从这些兰花中总共分离出12种新化合物（1 - 4、6 - 10、12、14、16）和5种已知化合物（5、11、13、15、17）。化合物1 - 8是被一个或两个4 - 羟基苄基部分取代的芪类化合物。芪类化合物上的这种取代类型并不常见，仅被报道过两次。结构解析基于光谱分析。