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[寰枢椎结核的定性诊断与治疗策略]

[Qualitative diagnosis and therapeutic strategy of atlanto-axial tuberculosis].

作者信息

Liu Xiao-guang, Wang Chao, Liu Zhong-jun, Dang Geng-ting

机构信息

Department of Orthopaedics, Peking University Third Hospital, Beijing 100083, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2007 Mar 15;45(6):409-11.

Abstract

OBJECTIVE

To investigate the qualitative diagnosis method of atlanto-axial tuberculosis and the corresponding therapeutic strategy.

METHODS

Twenty-two cases with atlanto-axial tuberculosis proven by histopathologic diagnosis were observed. Three cases and 17 cases underwent trans-oral biopsy and CT-guide percutaneous biopsy respectively, 2 cases were conformed by frozen section in operation. Thirteen of the 22 cases underwent surgical therapy: 1 case with anterior trans-oral radical eradication and fusion under Halo-vest immobilization, 7 cases with anterior cervical radical eradication, 1 case with anterior interbody fusion and titanic plate fixation, 2 cases were with posterior atlantoaxial interlaminar fusion and 2 cases with posterior cervical occipito-axial titanic plate internal fixation and fusion. Other 9 cases accepted nonsurgical therapy: 8 cases with Halo-vest immobilization and 1 case with head halter traction. All cases were given appropriate antituberculotic chemotherapy for 12-18 months.

RESULTS

All of the 22 cases were followed up, and the average time was 37 month. The lesion focus showed reparation and fusion in X-ray, and the results were satisfactory.

CONCLUSIONS

Biopsy can acquire the qualitative diagnosis on atlanto-axial tuberculosis. The choice of therapy is made on the situation of cold abscess, pathological fracture, atlanto-axial dislocation and spinal cord compression.

摘要

目的

探讨寰枢椎结核的定性诊断方法及相应的治疗策略。

方法

观察经组织病理学确诊的22例寰枢椎结核患者。其中3例和17例分别接受经口活检和CT引导下经皮穿刺活检,2例术中经冰冻切片确诊。22例患者中13例行手术治疗:1例行前路经口病灶清除并在头环背心固定下融合,7例行颈前路病灶清除,1例行前路椎间融合并钛板固定,2例行后路寰枢椎椎板间融合,2例行后路颈枕枢钛板内固定融合。另外9例接受非手术治疗:8例行头环背心固定,1例行头颅牵引。所有病例均给予适当的抗结核化疗12 - 18个月。

结果

22例患者均获随访,平均随访时间37个月。X线显示病灶修复融合,效果满意。

结论

活检可对寰枢椎结核做出定性诊断。治疗方案根据寒性脓肿、病理性骨折、寰枢椎脱位及脊髓受压情况选择。

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