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联合心内膜和心外膜射频改良迷宫手术治疗心房颤动

[Combined endocardial and epicardial radiofrequency modified Maze procedure in the treatment of atrial fibrillation].

作者信息

Wang Jian-gang, Meng Xu, Li Hui, Cui Yong-qiang, Hou Xiao-tong, Gao Feng, Zheng Si-hong, Xu Chun-lei

机构信息

Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2007 Mar 15;45(6):415-8.

Abstract

OBJECTIVE

To evaluate the effectiveness of the combined endocardial and epicardial saline-irrigated radiofrequency modified maze procedure for the treatment of atrial fibrillation (AF).

METHODS

During a period of 3 years, 295 patients with AF having concomitant cardiac surgery underwent the procedure. Patients underwent either the endocardial and epicardial group (n=185) or the endocardial group (n=110) radiofrequency ablation. There were 124 males, 171 females with a mean age of (52 +/- 11) year old. Mean duration of preoperative AF was 36 +/- 43 months. And about 90.8 percent valve pathology was rheumatic. Valve operation was performed in 289 patients, coronary artery bypass graft surgery in 19 patients and congenital heart disease operation in 6 patients respectively. Follow-up for the whole patients ranged from 3 to 47 months (mean 28 +/- 5 months).

RESULTS

Ten patients died postoperatively (3.4%). Four patients died of low cardiac output, five patients died of multisystem and organ failure, one patient died of cerebral hernia. There were 2 patients died of nerves system complication during follow-up. At the end of the procedure 228 patients (77.3%) were sinus rhythm, including 78 patients (70.9%) in endocardial group while 150 patients (81.1%) in endocardial and epicardial group (P<0.05). At late follow-up, 191 of 259 patients (73.7%) were in stable sinus rhythm. Sinus rhythm was present in 64 patients (66.0%) in endocardial group while 127 patients (78.4%) in endocardial and epicardial group (P<0.05). Histopathology of the endocardial group revealed foci coagulative necrosis was limited to the endocardial side. While endocardial and epicardial ablation had full-thickness alteration of atrial tissue besides ill defined borders and inflammatory cell infiltration.

CONCLUSIONS

Combined endocardial and epicardial saline-irrigated radiofrequency modified maze procedure was performed safely and efficiently. And it restored sinus rhythm better than endocardial ablation only.

摘要

目的

评估心内膜和心外膜盐水灌注射频改良迷宫手术治疗心房颤动(AF)的有效性。

方法

在3年期间,295例合并心脏手术的AF患者接受了该手术。患者接受心内膜和心外膜组(n = 185)或心内膜组(n = 110)的射频消融。男性124例,女性171例,平均年龄(52±11)岁。术前AF的平均持续时间为36±43个月。约90.8%的瓣膜病变为风湿性。分别有289例患者进行了瓣膜手术,19例患者进行了冠状动脉旁路移植术,6例患者进行了先天性心脏病手术。所有患者的随访时间为3至47个月(平均28±5个月)。

结果

10例患者术后死亡(3.4%)。4例死于低心排血量,5例死于多系统和器官衰竭,1例死于脑疝。随访期间有2例死于神经系统并发症。手术结束时,228例患者(77.3%)为窦性心律,其中心内膜组78例(70.9%),心内膜和心外膜组150例(81.1%)(P<0.05)。在晚期随访中,259例患者中有191例(73.7%)为稳定窦性心律。心内膜组64例患者(66.0%)为窦性心律,心内膜和心外膜组127例患者(78.4%)为窦性心律(P<0.05)。心内膜组的组织病理学显示凝固性坏死灶仅限于心内膜侧。而心内膜和心外膜消融除了边界不清和炎症细胞浸润外,心房组织有全层改变。

结论

心内膜和心外膜盐水灌注射频改良迷宫手术安全有效。并且它恢复窦性心律的效果优于单纯的心内膜消融。

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