多感官整合缩短生理反应潜伏期。
Multisensory integration shortens physiological response latencies.
作者信息
Rowland Benjamin A, Quessy Stephan, Stanford Terrence R, Stein Barry E
机构信息
Department of Neurobiology and Anatomy, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
出版信息
J Neurosci. 2007 May 30;27(22):5879-84. doi: 10.1523/JNEUROSCI.4986-06.2007.
Abstract
Individual superior colliculus (SC) neurons integrate information from multiple sensory sources to enhance their physiological response. The response of an SC neuron to a cross-modal stimulus combination can not only exceed the best component unisensory response but can also exceed their arithmetic sum (i.e., superadditivity). The present experiments were designed to investigate the temporal profile of multisensory integration in this model system. We found that cross-modal stimuli frequently shortened physiological response latencies (mean shift, 6.2 ms) and that response enhancement was greatest in the initial phase of the response (the phenomenon of initial response enhancement). The vast majority of the responses studied evidenced superadditive computations, most often at the beginning of the multisensory response.
摘要
单个上丘（SC）神经元整合来自多个感觉源的信息，以增强其生理反应。SC神经元对跨模态刺激组合的反应不仅可以超过最佳单感觉成分反应，而且还可以超过它们的算术和（即超相加性）。本实验旨在研究该模型系统中多感觉整合的时间特征。我们发现跨模态刺激经常缩短生理反应潜伏期（平均偏移6.2毫秒），并且反应增强在反应的初始阶段最大（初始反应增强现象）。所研究的绝大多数反应都证明了超相加性计算，最常见于多感觉反应开始时。
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