Qiao Aike, Matsuzawa Teruo
Center for Information Science, Japan Advanced Institute of Science and Technology, Japan.
Biorheology. 2007;44(2):103-24.
The effectiveness of femoral bypass grafts is correlated with the geometric configuration and hemodynamics of the bypass and the arteries. As an attempt to develop a new design for femoral bypass grafts, we present a novel geometric configuration for a symmetrically implanted 2-way bypass graft. In order to investigate how the symmetric 2-way bypass grafts affect the flow patterns through the anastomosis, physiologic blood flows in 1-way and 2-way models for a fully stenosed femoral bypass were simulated with the finite element method, and the hemodynamic factors in these models were studied. The temporal and spatial distributions of flow patterns and wall shear stresses in the vicinity of distal anastomosis during the cardiac cycle were analyzed. The results computed showed that the 2-way model has more preferable hemodynamics than the 1-way model in the distribution of flow patterns and wall shear stresses, and it may improve the flow conditions and decrease the probability of restenosis. However, the limitations of the 2-way bypass model may counteract the positive effects. More detailed hemodynamic studies are necessary to fully assess the viability of the 2-way bypass graft.
股动脉搭桥移植物的有效性与搭桥移植物及动脉的几何结构和血流动力学相关。作为开发新型股动脉搭桥移植物设计的一种尝试，我们提出了一种用于对称植入的双向搭桥移植物的新型几何结构。为了研究对称双向搭桥移植物如何影响通过吻合口的血流模式，采用有限元方法模拟了完全狭窄股动脉搭桥的单向和双向模型中的生理血流，并研究了这些模型中的血流动力学因素。分析了心动周期期间远端吻合口附近血流模式和壁面剪应力的时空分布。计算结果表明，在血流模式和壁面剪应力分布方面，双向模型比单向模型具有更优的血流动力学特性，并且它可能改善血流状况并降低再狭窄的概率。然而，双向搭桥模型的局限性可能会抵消其积极作用。需要进行更详细的血流动力学研究以全面评估双向搭桥移植物的可行性。
