Siniscalchi Enrico Nastro, Angileri Filippo Flavio, Mastellone Paola, Catalfamo Luciano, Giusa Maria, Conti Alfredo, De Ponte Francesco Saverio, Tomasello Francesco
Department of Maxillo-Facial Surgery and the Department of Neurosurgery, University of Messina, Messina, Italy.
J Craniofac Surg. 2007 May;18(3):622-5. doi: 10.1097/scs.0b013e318052ff6c.
Excision of neoplasm and trauma involving the anterior cranial base may often result in communication between the intracranial and extracranial compartments. Many techniques have been proposed to obtain a watertight separation. We report our 5 years of experience in the management of anterior skull base defects using a galeal-pericranial flap. Between January 2001 and April 2006, 22 patients were treated for a cranial base reconstruction at the University of Messina. Five of them presented with persistent cerebrospinal fluid (CSF) leak after previous craniofacial trauma. Ten underwent a combined maxillofacial-neurosurgical approach for the removal of a benign tumor involving the anterior skull base. Seven had severe craniofacial trauma, which required an intervention of reconstruction of the anterior skull base. In the whole series, a galeal-pericranial flap was used to separate intra- and extracranial compartments. No patients developed postoperative brain contusions or subdural-epidural blood collections. Throughout the follow-up period, there was no evidence of flap failure. In all but one patient, no postoperative CSF leak was evident. In one patient, a mild transient postoperative CSF leakage was present. There has been no recurrent CSF leak or meningitis. The follow up average of 23 months shows no incidence of infection. Even if our series does not comprise malignancies and previously irradiated patients, our data confirm the validity of the galeal- pericranial flap for the surgical management of minimal and moderately sized defects of anterior cranial base.
前颅底肿瘤切除及外伤常可导致颅内与颅外腔隙相通。人们已提出多种技术来实现水密性分隔。我们报告了使用帽状腱膜-颅骨膜瓣治疗前颅底缺损的5年经验。2001年1月至2006年4月期间,墨西拿大学对22例患者进行了颅底重建治疗。其中5例在先前颅面外伤后出现持续性脑脊液(CSF)漏。10例接受了颌面-神经外科联合手术,以切除累及前颅底的良性肿瘤。7例有严重颅面外伤,需要进行前颅底重建干预。在整个系列中,使用帽状腱膜-颅骨膜瓣来分隔颅内和颅外腔隙。没有患者发生术后脑挫伤或硬膜下-硬膜外血肿。在整个随访期间,没有证据表明皮瓣失败。除1例患者外,所有患者术后均未出现明显的脑脊液漏。1例患者术后出现轻度短暂性脑脊液漏。没有复发性脑脊液漏或脑膜炎。平均23个月的随访显示无感染发生。即使我们的系列研究不包括恶性肿瘤患者和先前接受过放疗的患者,我们的数据仍证实了帽状腱膜-颅骨膜瓣用于手术治疗前颅底轻度和中度大小缺损的有效性。