枕下开颅术后28年发生颈椎肿瘤性焦磷酸钙二水合物沉积病：病例报告
Cervical tumoral calcium pyrophosphate dihydrate deposition disease 28 years after suboccipital craniotomy: case report.
作者信息
Scavarda Didier, Litre Claude F, Froelich Stéphane, Srour Robin, Rousseaux Pascal
机构信息
Department of Pediatric Neurosurgery, Children's Hospital, La Timone, Marseille, France.
出版信息
Neurosurgery. 2007 Jun;60(6):E1151; discussion E1151. doi: 10.1227/01.NEU.0000255477.06247.B8.
OBJECTIVE
To describe a rare case of tumoral cervical chondrocalcinosis that appeared 28 years after the patient had undergone suboccipital craniotomy.
CLINICAL PRESENTATION
A 42-year-old woman suffered from cervicalgia associated with a firm mass at the occipitocervical region. Plain x-ray and computed tomographic and magnetic resonance images revealed a calcified lesion in a scar from a previous suboccipital craniotomy.
INTERVENTION
The patient underwent tumorectomy and histopathology, which revealed an exuberant tumoral chondrocalcinosis. Laboratory test results revealed no secondary cause for the chondrocalcinosis.
CONCLUSION
Identification of chondrocalcinosis beyond the cervical region is very rare. Localization of chondrocalcinosis in a scar from a previous suboccipital craniotomy has not been previously reported. Surgery appears to be the treatment of choice for this form of chondrocalcinosis.
目的
描述一例罕见的肿瘤性颈椎软骨钙质沉着症病例，该病例在患者接受枕下开颅术后28年出现。
临床表现
一名42岁女性患有颈痛，枕颈部有一质地坚硬的肿块。X线平片、计算机断层扫描和磁共振成像显示，在既往枕下开颅手术的瘢痕处有一钙化病变。
干预措施
患者接受了肿瘤切除术及组织病理学检查，结果显示为增生性肿瘤性软骨钙质沉着症。实验室检查结果未发现导致软骨钙质沉着症的继发原因。
结论
颈椎区域以外的软骨钙质沉着症非常罕见。软骨钙质沉着症定位于既往枕下开颅手术的瘢痕处此前未见报道。手术似乎是这种类型软骨钙质沉着症的首选治疗方法。
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