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水痘后重症肌无力

Post-varicella myasthenia gravis.

作者信息

Saha A, Batra P, Vilhekar K Y, Chaturvedi P

机构信息

Department of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India.

出版信息

Singapore Med J. 2007 Jun;48(6):e177-80.

Abstract

Myasthenia gravis is an autoimmune disease of neuromuscular junctions. We report a three-year-old boy with post-varicella myasthenia gravis. This patient, to the best of our knowledge, is the youngest in age and second reported case of the condition. The patient presented with drooping of both eyelids which increased as the day progressed, two weeks after varicella infection. Repetitive nerve stimulation tests showed decremental response in action potential, and the child responded dramatically to test doses of neostigmine. A diagnosis of post-varicella myasthenia gravis was made and the patient was started on oral pyridostigmine. He is doing well at follow-up and there is no recurrence of symptoms to date.

摘要

重症肌无力是一种神经肌肉接头处的自身免疫性疾病。我们报告了一名患有水痘后重症肌无力的三岁男孩。据我们所知,该患者是年龄最小且第二例报告的该病症病例。该患者在水痘感染两周后出现双侧眼睑下垂,且随着一天时间的推移而加重。重复神经电刺激试验显示动作电位递减反应,并且该患儿对新斯的明试验剂量反应显著。诊断为水痘后重症肌无力,患者开始口服吡啶斯的明。随访时他情况良好,迄今为止症状未复发。

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