Pardini M, Bonzano L, Roccatagliata L, Boccardo F, Mancardi G, Campisi C
Magnetic Resonance Research Centre on Nervous System Diseases, University School of Medicine and Surgery, San Martino Hospital, Genoa, Italy.
Lymphology. 2007 Mar;40(1):19-25.
We report the first application of brain functional Magnetic Resonance Imaging (fMRI) to congenital peripheral lymphedema patients before and after microsurgical treatment. Our aim was to evaluate the effects of limb shape change on cortical organization of the motor system and how the cortical sensorimotor network restructures after microsurgical therapy. We acquired fMRI during active motor and motor imagery tasks before surgery and six months after surgery in a patient with congenital lymphedema of the left leg. fMRI data revealed activation differences in primary and secondary motor areas between the two scanning sessions for both tasks and also between the patient's and a healthy volunteer's activations. We suggest that these alterations could be related to changes in body schema representation due to the congenital lymphedema.
我们报告了脑功能磁共振成像（fMRI）首次应用于先天性周围性淋巴水肿患者显微外科治疗前后的情况。我们的目的是评估肢体形状改变对运动系统皮质组织的影响，以及显微外科治疗后皮质感觉运动网络如何重构。我们对一名左腿先天性淋巴水肿患者在手术前和术后六个月进行主动运动和运动想象任务时采集了fMRI数据。fMRI数据显示，两项任务在两次扫描之间以及患者与健康志愿者激活之间，初级和次级运动区均存在激活差异。我们认为，这些改变可能与先天性淋巴水肿导致的身体图式表征变化有关。
