Yang Chih-Jen, Chen Tun-Chieh, Hung Jen-Yu, Lu Po-Liang, Sheu Chau-Chyun, Tsai Jong-Rung, Chong Inn-Wen, Hwang Jhi-Jhu, Huang Ming-Shyan
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical Uniersity Hospital, Kaohsiung, Taiwan.
Respirology. 2007 May;12(3):412-5. doi: 10.1111/j.1440-1843.2007.01072.x.
The value of routine culture for mycobacterium from bronchoscopic washings and the cost-effectiveness is still uncertain in countries where tuberculosis is endemic. This study examined the epidemiology of positive cultures for M. tuberculosis obtained by bronchoscopy to determine the health benefit and cost of a policy of routine culture and smear.
All positive cultures for Mycobacterium tuberculosis in bronchial washings and the corresponding CXR features were analysed.
The incidence of tuberculosis in routine bronchoscopy was 3.71%, and in patients who presented with typical tuberculosis features on CXR was 6.5%. Up to 10.6% of culture-proven pulmonary tuberculosis relied on bronchoscopy for diagnosis. The total cost of routine mycobacterium culture and acid-fast bacillus smear during the 2-year period was approximately US $24,800.
Routine mycobacterium culture and acid-fast staining from bronchoscopic specimens appears to be valuable in countries where tuberculosis is prevalent.
在结核病流行的国家，支气管灌洗标本常规进行分枝杆菌培养的价值及其成本效益仍不明确。本研究通过分析经支气管镜检查获得的结核分枝杆菌阳性培养物的流行病学情况，以确定常规培养和涂片策略的健康效益及成本。
分析支气管灌洗中所有结核分枝杆菌阳性培养物及相应的胸部X线特征。
常规支气管镜检查中结核病的发病率为3.71%，胸部X线表现为典型结核病特征的患者中发病率为6.5%。经培养证实的肺结核中，高达10.6%依靠支气管镜检查进行诊断。两年期间常规分枝杆菌培养和抗酸杆菌涂片的总成本约为24,800美元。
在结核病流行的国家，支气管镜标本进行常规分枝杆菌培养和抗酸染色似乎具有重要价值。
