Lee Yuan-Chieh, Chung Fang-Ling, Chen Chien-Chung
Department of Ophthalmology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Am J Ophthalmol. 2007 Aug;144(2):203-208. doi: 10.1016/j.ajo.2007.04.020. Epub 2007 May 30.
To evaluate the natural course of intraocular pressure (IOP) and foveal thickness during the postoperative period, and the correlation between them.
Prospective observational case series.
This institutional study comprised 30 eyes of 30 cataract patients scheduled for phacoemulsification. IOP and foveal thickness by optical coherence tomography (OCT) were measured preoperatively and three, six, nine, 12, 15, 18, 21, 24 hours, five days, one month, and two months postoperatively.
The IOP was 4.7 +/- 2.4 mm Hg at three hours postoperatively. The IOP increased to 23.4 +/- 8.1 mm Hg at six hours and 23.5 +/- 7.3 mm Hg at nine hours postoperatively. The IOP was 1.9 mm Hg lower at one month or two months postoperatively than preoperatively. The foveal thickness was 202.1 +/- 19.2 microm and significantly higher at three hours postoperatively, and was 182.3 +/- 20.5 microm, 183.2 +/- 22.3 microm, and significantly lower at nine and 12 hours postoperatively than preoperatively. The correlation between mean IOP and mean foveal thickness is statistically significant. Fovea thickness (microns) = 207.0476 - 1.019759 x IOP (mm Hg), P value < .0001, adjusted R(2) = .8699.
We found initial hypotony, an IOP spike during six to nine hours, and a decrease of IOP at one month and two months postoperatively. An initial increase of the foveal thickness, a significant reduction at nine hours and 12 hours, and an equivocal increase at one month or two months postoperatively were also noted. A significant negative correlation between IOP and foveal thickness was shown.
评估术后眼压（IOP）和黄斑中心凹厚度的自然病程及其相关性。
前瞻性观察病例系列。
本机构研究纳入了30例计划行超声乳化白内障吸除术的白内障患者的30只眼。术前及术后3、6、9、12、15、18、21、24小时、5天、1个月和2个月，通过光学相干断层扫描（OCT）测量眼压和黄斑中心凹厚度。
术后3小时眼压为4.7±2.4 mmHg。术后6小时眼压升至23.4±8.1 mmHg，9小时为23.5±7.3 mmHg。术后1个月或2个月时眼压较术前低1.9 mmHg。黄斑中心凹厚度术前为202.1±19.2微米，术后3小时显著升高，术后9小时和12小时分别为182.3±20.5微米和183.2±22.3微米，显著低于术前。平均眼压与平均黄斑中心凹厚度之间的相关性具有统计学意义。黄斑中心凹厚度（微米）=207.0476 - 1.019759×眼压（mmHg），P值<0.0001，调整后R² = 0.8699。
我们发现术后初期眼压降低，6至9小时出现眼压峰值，术后1个月和2个月眼压下降。还观察到黄斑中心凹厚度初期增加，9小时和12小时显著降低，术后1个月或2个月变化不明确。眼压与黄斑中心凹厚度之间存在显著负相关。
