• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

间碘酰基苯甲酸——一种用于高效芳香族碘化反应的便捷可回收试剂。

m-Iodosylbenzoic acid - a convenient recyclable reagent for highly efficient aromatic iodinations.

作者信息

Kirschning Andreas, Yusubov Mekhman S, Yusubova Roza Y, Chi Ki-Whan, Park Joo Y

机构信息

Institut für Organische Chemie and Zentrum für Biomolekulare Wirkstoffchemie (BMWZ), Leibniz Universität Hannover, Schneiderberg 1B, D-30167 Hannover, Germany.

出版信息

Beilstein J Org Chem. 2007 Jun 4;3:19. doi: 10.1186/1860-5397-3-19.

DOI:10.1186/1860-5397-3-19
PMID:17543133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1924527/
Abstract

m-Iodosylbenzoic acid performs iodinations of arenes in the presence of iodine at room temperature in acetonitrile. Separation of pure products is conveniently achieved by scavenging any aryl iodide by ion exchange with IRA-900 (hydroxide form). The reduced form of the reagent, m-iodobenzoic acid, can be easily recovered from the ion exchange resin or from the basic aqueous solution by simple acidification with HCl.

摘要

间碘酰基苯甲酸在室温下于乙腈中，在碘存在的情况下对芳烃进行碘化反应。通过用IRA - 900（氢氧化物形式）进行离子交换清除任何芳基碘化物，可方便地实现纯产物的分离。试剂的还原形式，间碘苯甲酸，可通过用盐酸简单酸化，轻松地从离子交换树脂或碱性水溶液中回收。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61f/1924527/504ef2139fdf/Beilstein_J_Org_Chem-03-19-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61f/1924527/5eba3ecd6c68/Beilstein_J_Org_Chem-03-19-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61f/1924527/26f95ac3c56a/Beilstein_J_Org_Chem-03-19-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61f/1924527/504ef2139fdf/Beilstein_J_Org_Chem-03-19-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61f/1924527/5eba3ecd6c68/Beilstein_J_Org_Chem-03-19-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61f/1924527/26f95ac3c56a/Beilstein_J_Org_Chem-03-19-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61f/1924527/504ef2139fdf/Beilstein_J_Org_Chem-03-19-g004.jpg

相似文献

1
m-Iodosylbenzoic acid - a convenient recyclable reagent for highly efficient aromatic iodinations.间碘酰基苯甲酸——一种用于高效芳香族碘化反应的便捷可回收试剂。
Beilstein J Org Chem. 2007 Jun 4;3:19. doi: 10.1186/1860-5397-3-19.
2
Preparation and X-ray structures of 3-[Bis(trifluoroacetoxy)iodo]benzoic acid and 3-[hydroxy(tosyloxy)iodo]benzoic acid: new recyclable hypervalent iodine reagents.3-[双(三氟乙酰氧基)碘]苯甲酸和3-[羟基(对甲苯磺酰氧基)碘]苯甲酸的制备及X射线结构：新型可循环使用的高价碘试剂
J Org Chem. 2008 Jan 4;73(1):295-7. doi: 10.1021/jo702112s. Epub 2007 Dec 7.
3
Preparation, Structure, and Reactivity of Pseudocyclic Benziodoxole Tosylates: New Hypervalent Iodine Oxidants and Electrophiles.对甲苯磺酸假环苯并碘杂氧戊环酯的制备、结构与反应活性：新型高价碘氧化剂和亲电试剂
Chemistry. 2017 Jan 12;23(3):691-695. doi: 10.1002/chem.201604475. Epub 2016 Dec 1.
4
Preparation, X-ray structure, and reactivity of 2-iodylpyridines: recyclable hypervalent iodine(V) reagents.2-碘吡啶的制备、X 射线结构和反应性：可回收高价碘(V)试剂。
J Org Chem. 2011 May 20;76(10):3812-9. doi: 10.1021/jo200163m. Epub 2011 Apr 14.
5
Photocatalytic dehalogenation coupled on-line to a reversed micellar-mediated chemiluminescence detection system: application to the determination of iodinated aromatic compounds.光催化脱卤与反胶束介导的化学发光检测系统在线联用：用于测定碘化芳香族化合物
Anal Chem. 2003 Sep 1;75(17):4493-8. doi: 10.1021/ac030004x.
6
Synthesis of NH-Sulfoximines by Using Recyclable Hypervalent Iodine(III) Reagents under Aqueous Micellar Conditions.在水胶束条件下使用可回收高价态碘(III)试剂合成 NH-亚磺酰基化合物。
ChemSusChem. 2020 Mar 9;13(5):922-928. doi: 10.1002/cssc.201903430. Epub 2020 Feb 11.
7
Hypervalent Iodine Mediated Chemoselective Iodination of Alkynes.高价碘介导的炔烃化学选择性碘化反应。
J Org Chem. 2017 Nov 17;82(22):11865-11871. doi: 10.1021/acs.joc.7b01555. Epub 2017 Aug 29.
8
An ion-exchange method for selective separation of palladium, platinum and rhodium from solutions obtained by leaching automotive catalytic converters.一种从汽车催化转化器浸出所得溶液中选择性分离钯、铂和铑的离子交换方法。
Talanta. 1995 Feb;42(2):249-55. doi: 10.1016/0039-9140(94)00246-o.
9
Convenient syntheses of fluorous aryl iodides and hypervalent iodine compounds: ArI(L)n reagents that are recoverable by simple liquid/liquid biphase workups, and applications in oxidations of hydroquinones.氟代芳基碘化物和高价碘化合物的简便合成：可通过简单液/液双相后处理回收的ArI(L)n试剂及其在对苯二酚氧化反应中的应用
Chemistry. 2003 Jan 3;9(1):88-95. doi: 10.1002/chem.200390034.
10
Catalytic hydrodechlorination of triclosan using a new class of anion-exchange-resin supported palladium catalysts.使用新型阴离子交换树脂负载钯催化剂催化水解三氯生。
Water Res. 2017 Sep 1;120:199-210. doi: 10.1016/j.watres.2017.04.059. Epub 2017 Apr 26.

引用本文的文献

1
Chemistry of polyvalent iodine.多价碘的化学性质
Chem Rev. 2008 Dec;108(12):5299-358. doi: 10.1021/cr800332c.

本文引用的文献

1
One- and Two-Dimensional Electron Transfer Processes in Triarylamines with Multiple Redox Centers.具有多个氧化还原中心的三芳基胺中的一维和二维电子转移过程。
Angew Chem Int Ed Engl. 1998 Aug 17;37(15):2107-2110. doi: 10.1002/(SICI)1521-3773(19980817)37:15<2107::AID-ANIE2107>3.0.CO;2-H.
2
Effect of water on the functionalization of substituted anisoles with iodine in the presence of F-TEDA-BF4 or hydrogen peroxide.在F-TEDA-BF4或过氧化氢存在下，水对碘代取代苯甲醚官能化的影响。
J Org Chem. 2006 Feb 3;71(3):1027-32. doi: 10.1021/jo052021n.
3
Rational synthesis of meso- or beta- fluoroalkylporphyrin derivatives via halo-fluoroalkylporphyrin precursors: electronic and steric effects on regioselective electrophilic substitution in 5-fluoroalkyl-10,20-diarylporphyrins.
通过卤代氟烷基卟啉前体合理合成内消旋或β-氟烷基卟啉衍生物：5-氟烷基-10,20-二芳基卟啉区域选择性亲电取代的电子和空间效应
J Org Chem. 2006 Jan 20;71(2):527-36. doi: 10.1021/jo051672g.
4
Synthesis and functionalization of indoles through palladium-catalyzed reactions.通过钯催化反应合成吲哚及其官能团化
Chem Rev. 2005 Jul;105(7):2873-920. doi: 10.1021/cr040639b.
5
Organohypervalent iodine: development, applications, and future directions.有机高价碘：发展、应用及未来方向。
J Org Chem. 2005 Apr 15;70(8):2893-903. doi: 10.1021/jo050117b.
6
Introduction of a third meso substituent into 5,10-diaryl chlorins and oxochlorins.将第三个中位取代基引入5,10 - 二芳基二氢卟吩和氧化二氢卟吩中。
J Org Chem. 2005 Jan 7;70(1):275-85. doi: 10.1021/jo048440m.
7
New developments in polymer-supported reagents, scavengers and catalysts for organic synthesis.用于有机合成的聚合物负载试剂、清除剂和催化剂的新进展。
Curr Opin Drug Discov Devel. 2004 Nov;7(6):752-64.
8
Highly functionalized organomagnesium reagents prepared through halogen-metal exchange.通过卤素-金属交换制备的高官能化有机镁试剂。
Angew Chem Int Ed Engl. 2003 Sep 22;42(36):4302-20. doi: 10.1002/anie.200300579.
9
Tag strategy for separation and recovery.分离与回收的标签策略。
Chem Rev. 2002 Oct;102(10):3693-716. doi: 10.1021/cr0103524.
10
ROMPgel reagents in parallel synthesis.用于平行合成的ROMP凝胶试剂。
Chem Rev. 2002 Oct;102(10):3301-24. doi: 10.1021/cr0103423.