Sarkisian A A, Naumova V I, Sheliia N Sh, Sentsova T B, Gozalishvili T V
Pediatriia. 1991(7):21-4.
As many as 91 children with the nephrotic and hematuric forms of primary chronic glomerulonephritis were examined for the presence of streptococcal infection and allergic diseases. It has been shown that as compared to patients with the hematuric form of chronic glomerulonephritis, those with the nephrotic form manifest a higher occurrence of A3, a dramatic rise of serum IgE and its dependence on the activity of glomerulonephritis. The data obtained may attest to the etiological role played by allergy in the development of the nephrotic form of glomerulonephritis. Frequently occurring colonization of hemolytic streptococcus in the fauces and the rise of the ASL-O titer in the blood serum seen in patients with the hematuric form of glomerulonephritis, its dependence on the disease activity suggest the streptococcal etiology in patients with that form in contrast to those with the nephrotic form.
对多达91名患有原发性慢性肾小球肾炎肾病型和血尿型的儿童进行了链球菌感染和过敏性疾病检查。结果表明，与慢性肾小球肾炎血尿型患者相比，肾病型患者A3发生率更高，血清IgE显著升高且与肾小球肾炎活动度相关。所得数据可能证明过敏在肾小球肾炎肾病型发展中所起的病因学作用。血尿型肾小球肾炎患者中常见的咽峡部溶血性链球菌定植以及血清中抗链球菌溶血素O滴度升高，且其与疾病活动度相关，这表明该型患者与肾病型患者相比病因是链球菌感染。
