Horica C A, Pescia R, Akovbiantz A, Haemmerli U P, Jäger M, Landolt M, Schmid M, Weitzel M, Blum A L
Schweiz Med Wochenschr. 1975 Dec 13;105(50):1708-11.
To evaluate the presence or absence of hepatic metastases or primary hepatoma 106 patients were examined by liver scintigram as well as laparoscopy or laparotomy. A definite diagnosis was established in all patients by histology, autopsy or observation of clinical course for at least one year. Only scintigrams resulted in false positive diagnosis (in 5%). False negative diagnoses were obtained in 29% of laparoscopies and in 36% of scintigrams when evaluated routinely with knowledge of the clinical findings and laboratory examinations. Analysis of the same scintigrams by an experienced examiner without knowledge of the clinical findings lowered the proportion of false negative scintigrams to 12%. In 5 patients with liver metastases or hepatoma coexisting in liver cirrhosis or advanced chronic liver congestion, both methods of examination gave false negative results.
为评估肝转移瘤或原发性肝癌的有无，对106例患者进行了肝脏闪烁扫描以及腹腔镜检查或剖腹手术。所有患者均通过组织学、尸检或至少一年的临床病程观察得以确诊。仅闪烁扫描出现假阳性诊断（5%）。当结合临床发现和实验室检查结果进行常规评估时，腹腔镜检查有29%出现假阴性诊断，闪烁扫描有36%出现假阴性诊断。由一位不了解临床发现的经验丰富的检查者对相同的闪烁扫描结果进行分析，可将假阴性闪烁扫描的比例降至12%。在5例肝硬化或晚期慢性肝淤血合并肝转移瘤或肝癌的患者中，两种检查方法均给出了假阴性结果。
